Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04274179 · ClinicalTrials.gov registry record · Phase 3

Ketogenic Diet for New-Onset Absence Epilepsy

A Phase 3 study of Ketogenic Dieting and Epilepsy, Absence, sponsored by Johns Hopkins University.

Recruiting
Registry status
Phase 3
Development phase
40
Enrollment target
1
Study location

NCT04274179 is a Phase 3 study of Ketogenic Dieting and Epilepsy, Absence that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 40 participants, roughly in line with the 39-participant average among 5 other Ketogenic Dieting trials with a reported enrollment target. The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04274179, a Phase 3 study of Ketogenic Dieting and Epilepsy, Absence, is actively recruiting participants, sponsored by Johns Hopkins University.

RECRUITING
Registry status
Phase 3
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

The ketogenic diet is a medical therapy for epilepsy that is used nearly predominantly for refractory epilepsy (after 2-3 drugs have been tried and failed). However, there is both published evidence for first-line use (infantile spasms, Glut1 deficiency syndrome) and also anecdotal experience (families choosing to change the child's (or the family' own) diet rather than use anticonvulsant medications). Childhood absence epilepsy (refractory) has been published as being responsive to ketogenic diet therapy by the investigators' group previously. This is a small, prospective, 3 month trial to assess if using a modified Atkins diet is a feasible and effective option for new-onset childhood absence epilepsy. The investigators will compare to a group of children in which the parents have declined and chose to start anticonvulsant medications.

Interventions

  • OTHER Modified Atkins Diet
  • DRUG Absence epilepsy medications

Study Locations (1)

Maryland

  • Johns Hopkins Hospital - Baltimore

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2020-08-10
Est. Completion 2026-05-01
Phase Phase 3

Sponsor

Johns Hopkins University

1,448 total trials

What the Registry Record Tells You About NCT04274179

The ClinicalTrials.gov registry entry for NCT04274179 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 39-participant average among 5 other Ketogenic Dieting trials with a reported enrollment target. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Ketogenic Dieting appearing as the primary indexed condition, and to 2 interventions - of which Modified Atkins Diet is the first listed.

NCT04274179 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT04274179 about?

NCT04274179 is a clinical study titled "Ketogenic Diet for New-Onset Absence Epilepsy". The ketogenic diet is a medical therapy for epilepsy that is used nearly predominantly for refractory epilepsy (after 2-3 drugs have been tried and failed). However, there is both published evidence for first-line use (infantile spasms, Glut1 deficiency syndrome) and also anecdotal experience (famil...

What is the current status of trial NCT04274179?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 40 participants. The study started on 2020-08-10. Estimated completion is 2026-05-01.

What conditions does trial NCT04274179 study?

This clinical trial studies the following conditions: Ketogenic Dieting, Epilepsy, Absence, Absence Epilepsy.

What interventions are being tested in trial NCT04274179?

The interventions under investigation include: Modified Atkins Diet (OTHER), Absence epilepsy medications (DRUG).

Who is sponsoring clinical trial NCT04274179?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04274179 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Ketogenic Dieting

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.