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NCT04223531 · ClinicalTrials.gov registry record · NA
The Natriuretic Peptide Response to Saline Infusion
A NA study of Obesity, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT04223531 is a NA study of Obesity that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 18 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04223531, a NA study of Obesity, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective is to evaluate the overarching hypothesis that obese and black individuals have relatively lower circulating natriuretic peptide levels compared with lean and white individuals. Conventional clinical assays for measurement of circulating natriuretic peptides display substantial overlap, precluding determination of the basis of the relative natriuretic peptide deficiency previously observed in these groups. We will study lean or obese, black or white, healthy adult subjects with intravenous (IV) saline infusion as a stimulus for natriuretic peptide production and release. We will measure circulating levels of natriuretic peptide isoforms using mass spectrometry that allows the specific identification of proBNP 1-108 and its cleavage product BNP 1-32.
Conditions Studied
Interventions
- DRUG Normal Saline 0.9% Infusion Solution Bag
Study Locations (1)
Tennessee
- Vanderbilt Univeristy - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2020-10-26 |
| Est. Completion | 2022-06-17 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04223531
The ClinicalTrials.gov registry entry for NCT04223531 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (98% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Normal Saline 0.9% Infusion Solution Bag is the first listed.
NCT04223531 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT04223531 about?
NCT04223531 is a clinical study titled "The Natriuretic Peptide Response to Saline Infusion". The primary objective is to evaluate the overarching hypothesis that obese and black individuals have relatively lower circulating natriuretic peptide levels compared with lean and white individuals. Conventional clinical assays for measurement of circulating natriuretic peptides display substantial...
What is the current status of trial NCT04223531?
This trial is currently completed. It is a NA study. The enrollment target is 18 participants. The study started on 2020-10-26. Estimated completion is 2022-06-17.
What conditions does trial NCT04223531 study?
This clinical trial studies the following conditions: Obesity.
What interventions are being tested in trial NCT04223531?
The interventions under investigation include: Normal Saline 0.9% Infusion Solution Bag (DRUG).
Who is sponsoring clinical trial NCT04223531?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04223531 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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