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NCT04183166 · ClinicalTrials.gov registry record · Phase 1
A Clinical Trial Evaluating TG4050 in Head and Neck Cancer
A Phase 1 study of Squamous Cell Carcinoma of Head and Neck, sponsored by Transgene.
- Active
- Registry status
- Phase 1
- Development phase
- 80
- Enrollment target
- 14
- Study locations
NCT04183166: Active Phase 1 study of Squamous Cell Carcinoma of Head and Neck, sponsored by Transgene.
NCT04183166 is a Phase 1 study of Squamous Cell Carcinoma of Head and Neck that is active but no longer recruiting, run by Transgene. The registered enrollment target is 80 participants, below the 168-participant average among 37 other Squamous Cell Carcinoma of Head and Neck trials with a reported enrollment target (52% lower). The trial reports 14 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04183166, a Phase 1 study of Squamous Cell Carcinoma of Head and Neck, is active but no longer recruiting, sponsored by Transgene.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 80 participants
- Enrollment target
- 14
- Study locations
Study Summary
This is a multicenter, open-label, two arms, randomized, phase I/II study evaluating the safety and tolerability as well as some activity parameters of TG4050 in patients with squamous cell carcinoma of the head and neck (SCCHN).
Primary Outcome
Incidence of Adverse Event reported per CTCAE v5.
Conditions Studied
Interventions
- DRUG TG4050
Study Locations (14)
Other
- Hôpital Saint André - CHU de Bordeaux - Bordeaux
- Hôpital de la Timone - Marseille
- Institut Curie - Paris
- IUCT Toulouse - Toulouse
- Institut Gustave Roussy - Villejuif
- Hospital Universitari Vall d Hebrón - Barcelona
- Institut Català d Oncologia - Hospital Duran i Reynals - Barcelona
- Hospital Clínico San Carlos - Madrid
- Hospital Universitario La Paz - Madrid
- Hospital Regional Universitario de Málaga - Hospital Civil - Málaga
- Complejo Hospitalario Universitario de Santiago - Santiago de Compostela
- NHS Clatterbridge Cancer Center - Liverpool
- Aintree University Hospital NHS Fondation Trust - Liverpool
Florida
- Mayo Clinic Jacksonville - Jacksonville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2019-12-12 |
| Est. Completion | 2031-12-30 |
| Phase | Phase 1 |
What the registry record for NCT04183166 still lists
NCT04183166 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 168-participant average among 37 other Squamous Cell Carcinoma of Head and Neck trials with a reported enrollment target (52% lower).
The record links to 1 condition, with Squamous Cell Carcinoma of Head and Neck appearing as the primary indexed condition, and to 1 intervention - of which TG4050 is the first listed.
NCT04183166 lists 14 locations in 2 states (Other, Florida).
Frequently Asked Questions
What is clinical trial NCT04183166 about?
NCT04183166 is a clinical study titled "A Clinical Trial Evaluating TG4050 in Head and Neck Cancer". This is a multicenter, open-label, two arms, randomized, phase I/II study evaluating the safety and tolerability as well as some activity parameters of TG4050 in patients with squamous cell carcinoma of the head and neck (SCCHN).
What is the current status of trial NCT04183166?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2019-12-12. Estimated completion is 2031-12-30.
What conditions does trial NCT04183166 study?
This clinical trial studies the following conditions: Squamous Cell Carcinoma of Head and Neck.
What interventions are being tested in trial NCT04183166?
The interventions under investigation include: TG4050 (DRUG).
Who is sponsoring clinical trial NCT04183166?
This trial is sponsored by Transgene, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04183166 being conducted?
This trial has 14 study locations across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04183166's enrollment target sits among peer trials
80 17th of 37 higher than 21 of 37 other Squamous Cell Carcinoma of Head and Neck trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Squamous Cell Carcinoma of Head and Neck trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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