Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04160754 · ClinicalTrials.gov registry record · NA

Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change

A NA study of Substance Use and Alcohol Use, Underage, sponsored by University of Southern California.

Completed
Registry status
NA
Development phase
24
Enrollment target
1
Study location

NCT04160754: Completed NA study of Substance Use and Alcohol Use, Underage, sponsored by University of Southern California.

NCT04160754 is a NA study of Substance Use and Alcohol Use, Underage that has completed, run by University of Southern California. The registered enrollment target is 24 participants, below the 1,260-participant average among 88 other Substance Use trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04160754, a NA study of Substance Use and Alcohol Use, Underage, has completed, sponsored by University of Southern California.

COMPLETED
Registry status
NA
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

This study will be the first to explore mindfulness as a prevention intervention among transition age youth and those with previous involvement in the juvenile or criminal justice system with substance use problems and history of exposure to violence/trauma. The study will focus on preventing escalation of substance use (e.g., alcohol and marijuana), trauma symptoms, and recidivism by using an intervention to target self-regulation and executive functioning. Justice involved youth have higher rates of alcohol use and related consequences and higher rates of exposure to violence (Post Traumatic Stress Disorder) compared to their non-justice involved peers. Prior research has found aspects of self-regulation (emotion regulation, impulse control), stress, and craving to be important putative targets in reducing alcohol use. With high rates of recidivism and increased risk of long term problems associated with substance use, it is imperative to test interventions that can reach at risk youth and target both alcohol use and important psychological and neurocognitive self-regulation mechanisms. This study tests whether the use of Mindfulness-Based Relapse Prevention (MBRP) for at risk young adults results in changes in important self-regulation mechanisms and improved alcohol use outcomes. Individuals assigned to the experimental group will receive interventions normally provided at a community clinic and eight 1.5-hour group sessions of MBRP. Sessions will occur once per week. Each session will target a specific theme such as being aware of personal triggers, maintaining present focus, allowing or letting things be, responding to emotional and physical experiences in skillful ways, and recognizing intrusive thoughts. Further, each session will incorporate a mindfulness meditation technique. The central hypothesis will be tested through a focus on three specific aims: (1) Beta pilot testing and refining MBRP based on feedback from focus groups, (2) testing the efficacy

Primary Outcome

Substance use will be measured using time line follow back approach for 15 different substances. We will ask about days of use and number of times used for each substance in the past month

Interventions

  • BEHAVIORAL Mindfulness Based Relapse Prevention
  • BEHAVIORAL Control (CTL)

Study Locations (1)

California

  • University of Southern California, School of Social Work - Los Angeles

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2019-03-05
Est. Completion 2020-06-30
Phase NA
University of Southern California

617 total trials

What the finished NCT04160754 record still lists

NCT04160754 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,260-participant average among 88 other Substance Use trials with a reported enrollment target (98% lower).

The record links to 3 conditions, with Substance Use appearing as the primary indexed condition, and to 2 interventions - of which Mindfulness Based Relapse Prevention is the first listed.

NCT04160754 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT04160754 about?

NCT04160754 is a clinical study titled "Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change". This study will be the first to explore mindfulness as a prevention intervention among transition age youth and those with previous involvement in the juvenile or criminal justice system with substance use problems and history of exposure to violence/trauma. The study will focus on preventing escala...

What is the current status of trial NCT04160754?

This trial is currently completed. It is a NA study. The enrollment target is 24 participants. The study started on 2019-03-05. Estimated completion is 2020-06-30.

What conditions does trial NCT04160754 study?

This clinical trial studies the following conditions: Substance Use, Alcohol Use, Underage, Alcohol Problem Drinking.

What interventions are being tested in trial NCT04160754?

The interventions under investigation include: Mindfulness Based Relapse Prevention (BEHAVIORAL), Control (CTL) (BEHAVIORAL).

Who is sponsoring clinical trial NCT04160754?

This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04160754 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Substance Use

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04160754's enrollment target sits among peer trials

24 87th of 88 higher than 2 of 88 other Substance Use trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Substance Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02331979 · 24 participants · NA

    Improving Bladder Function in SCI by Neuromodulation

  • NCT03096197 · 24 participants · NA

    Exoskeleton and Spinal Cord Stimulation for SCI

  • NCT03223922 · 24 participants · NA

    Neurocognitive Functioning With Genu-Sparing Whole Brain Radiation Therapy for Brain Metastases

  • NCT03326921 · 24 participants · Phase 1

    HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04160754, the US trial registry maintained by the National Library of Medicine. NCT04160754 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.