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NCT04154293 · ClinicalTrials.gov registry record · Phase 2

A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Congenital Ichthyosis

A Phase 2 study, sponsored by LEO Pharma.

Completed
Registry status
Phase 2
Development phase
34
Enrollment target

NCT04154293 is a Phase 2 study that has completed, run by LEO Pharma. The registered enrollment target is 34 participants.

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The verdict

NCT04154293, a Phase 2 study, has completed, sponsored by LEO Pharma.

COMPLETED
Registry status
Phase 2
Development phase
34 participants
Enrollment target

Study Summary

The purpose of this study is to investigate the efficacy and safety of two concentrations of topically applied ointment formulation of isotretinoin called TMB-001 (0.05% and 0.1% isotretinoin) in subjects 9 years of age and older for the treatment of congenital ichthyosis (CI), including recessive X-linked ichthyosis (RXLI) and autosomal recessive congenital ichthyosis-lamellar ichthyosis (ARCI-LI) subtypes. Funding Source FDA-OOPD

Interventions

  • DRUG Isotretinoin
  • OTHER Vehicle

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2019-12-03
Est. Completion 2021-08-30
Phase Phase 2

Sponsor

LEO Pharma

65 total trials

What the Registry Record Tells You About NCT04154293

The ClinicalTrials.gov registry entry for NCT04154293 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is LEO Pharma, which has 65 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Isotretinoin is the first listed.

NCT04154293 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04154293 about?

NCT04154293 is a clinical study titled "A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Congenital Ichthyosis". The purpose of this study is to investigate the efficacy and safety of two concentrations of topically applied ointment formulation of isotretinoin called TMB-001 (0.05% and 0.1% isotretinoin) in subjects 9 years of age and older for the treatment of congenital ichthyosis (CI), including recessive X...

What is the current status of trial NCT04154293?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 34 participants. The study started on 2019-12-03. Estimated completion is 2021-08-30.

What interventions are being tested in trial NCT04154293?

The interventions under investigation include: Isotretinoin (DRUG), Vehicle (OTHER).

Who is sponsoring clinical trial NCT04154293?

This trial is sponsored by LEO Pharma, which has 65 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.