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ACTIVE NOT RECRUITING Phase 1

Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemia

NCT04150887 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of the study is to characterize safety and tolerability of cusatuzumab in combination with various therapies used to treat acute myeloid leukemia (AML).

Conditions Studied

Interventions

  • DRUG Venetoclax
  • DRUG Azacitidine
  • DRUG Cusatuzumab

Study Locations (20)

Other

  • Universitaetsklinik Hamburg-Eppendorf — Hamburg
  • Universitaetsklinikum Leipzig — Leipzig
  • Klinikum der Universitaet Muenchen — München
  • Szpital Uniwersytecki w Krakowie — Krakow
  • Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Lodzi — Lodz

New York

  • Roswell Park Cancer Institute — Buffalo
  • Weill Cornell Medicine — New York
  • Memorial Sloan Kettering Cancer Center — New York
  • University of Rochester — Rochester

Alberta

  • Tom Baker Cancer Centre — Calgary
  • University of Alberta Hospital — Edmonton

California

  • City of Hope — Duarte

Kentucky

  • Norton Cancer Institute — Louisville

Michigan

  • Barbara Ann Karmanos Cancer Institute — Detroit

Pennsylvania

  • University of Pittsburgh School of Medicine — Pittsburgh

Texas

  • The University of Texas MD Anderson Cancer Center — Houston

Trial Details

FieldValue
Enrollment Target 61 participants
Start Date 2019-12-23
Est. Completion 2026-05-15
Phase Phase 1

Sponsor

OncoVerity

2 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04150887

The ClinicalTrials.gov registry entry for NCT04150887 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 61 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is OncoVerity, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Leukemia, Myeloid, Acute appearing as the primary indexed condition, and to 3 interventions — of which Venetoclax is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04150887 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Other, New York, Alberta. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04150887 about?

NCT04150887 is a clinical study titled "Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemia". The purpose of the study is to characterize safety and tolerability of cusatuzumab in combination with various therapies used to treat acute myeloid leukemia (AML).

What is the current status of trial NCT04150887?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 61 participants. The study started on 2019-12-23. Estimated completion is 2026-05-15.

What conditions does trial NCT04150887 study?

This clinical trial studies the following conditions: Leukemia, Myeloid, Acute. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04150887?

The interventions under investigation include: Venetoclax (DRUG), Azacitidine (DRUG), Cusatuzumab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04150887?

This trial is sponsored by OncoVerity, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04150887 being conducted?

This trial has 20 study locations across California, Kentucky, Michigan, New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial