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NCT04133376 · ClinicalTrials.gov registry record · NA

Electronic Hookah and Endothelial Cell Function

A NA study of Smoking and Endothelial Dysfunction, sponsored by University of California, Los Angeles.

Completed
Registry status
NA
Development phase
33
Enrollment target
1
Study location

NCT04133376 is a NA study of Smoking and Endothelial Dysfunction that has completed, run by University of California, Los Angeles. The registered enrollment target is 33 participants, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04133376, a NA study of Smoking and Endothelial Dysfunction, has completed, sponsored by University of California, Los Angeles.

COMPLETED
Registry status
NA
Development phase
33 participants
Enrollment target
1
Study location

Study Summary

Electronic nicotine delivery systems (ENDS) are a rapidly growing global epidemic among adolescents and young adults. Unlike other ENDS such as e-cigarettes, e-hookahs are used through traditional water-pipes, allowing the vapor-containing nicotine, propylene glycol, glycerin, and flavorings-to pass through a water-filled basin, potentially altering the vapor, before it is inhaled through the user's mouth. Contributing to e-hookahs popularity is the belief that the flavored smoke is detoxified as it passes through the water-filled basin, rendering e-hookah a safer tobacco alternative. However, an e-hookahs deliver flavored nicotine by creating a vapor of fine particles and volatile organic compounds that could induce vascular toxicity. While e-hookah vaping acutely reduces endothelial function, the specific role of nicotine and the mechanisms by which it may impairs endothelial function remain understudied. The objective of this project is to investigate the specific role of nicotine in mediating the acute effects of e-hookah vaping on endothelial dysfunction.

Interventions

  • OTHER Electronic hookah vaping with nicotine
  • OTHER Electronic hookah vaping without nicotine

Study Locations (1)

California

  • University of California, Los Angeles - Los Angeles

Trial Details

FieldValue
Enrollment Target 33 participants
Start Date 2020-01-16
Est. Completion 2023-05-29
Phase NA

What the Registry Record Tells You About NCT04133376

The ClinicalTrials.gov registry entry for NCT04133376 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 33 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (93% lower). The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Smoking appearing as the primary indexed condition, and to 2 interventions - of which Electronic hookah vaping with nicotine is the first listed.

NCT04133376 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT04133376 about?

NCT04133376 is a clinical study titled "Electronic Hookah and Endothelial Cell Function". Electronic nicotine delivery systems (ENDS) are a rapidly growing global epidemic among adolescents and young adults. Unlike other ENDS such as e-cigarettes, e-hookahs are used through traditional water-pipes, allowing the vapor-containing nicotine, propylene glycol, glycerin, and flavorings-to pass...

What is the current status of trial NCT04133376?

This trial is currently completed. It is a NA study. The enrollment target is 33 participants. The study started on 2020-01-16. Estimated completion is 2023-05-29.

What conditions does trial NCT04133376 study?

This clinical trial studies the following conditions: Smoking, Endothelial Dysfunction.

What interventions are being tested in trial NCT04133376?

The interventions under investigation include: Electronic hookah vaping with nicotine (OTHER), Electronic hookah vaping without nicotine (OTHER).

Who is sponsoring clinical trial NCT04133376?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04133376 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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