Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 1

A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma

NCT04106219 · View on ClinicalTrials.gov ↗

Study Summary

The reason for this study is to see if the study drug LY3295668 erbumine is safe in participants with relapsed/refractory neuroblastoma.

Conditions Studied

Interventions

  • DRUG Cyclophosphamide
  • DRUG Topotecan
  • DRUG LY3295668 Erbumine

Study Locations (17)

Other

  • Institut Curie — Paris
  • Universitätsklinikum Köln — Cologne
  • Hospital Infantil Universitario Niño Jesús — Madrid
  • Alder Hey Children's Hospital — Liverpool

California

  • UCSF Medical Center at Mission Bay — San Francisco

Colorado

  • Children's Hospital Colorado — Aurora

Illinois

  • University of Chicago - Comer Children's Hospital — Chicago

Massachusetts

  • Dana-Farber Cancer Institute — Boston

Ohio

  • Cincinnati Childrens Hospital Medical Center — Cincinnati

Pennsylvania

  • Children's Hospital of Philadelphia — Philadelphia

Texas

  • Texas Childrens Hospital — Houston

Trial Details

FieldValue
Enrollment Target 71 participants
Start Date 2020-06-11
Est. Completion 2026-08
Phase Phase 1

Sponsor

Eli Lilly and Company

704 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04106219

The ClinicalTrials.gov registry entry for NCT04106219 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 71 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Neuroblastoma appearing as the primary indexed condition, and to 3 interventions — of which Cyclophosphamide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04106219 reports 17 study locations spanning 14 distinct geographic areas — top geographies include Other, California, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04106219 about?

NCT04106219 is a clinical study titled "A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma". The reason for this study is to see if the study drug LY3295668 erbumine is safe in participants with relapsed/refractory neuroblastoma.

What is the current status of trial NCT04106219?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 71 participants. The study started on 2020-06-11. Estimated completion is 2026-08.

What conditions does trial NCT04106219 study?

This clinical trial studies the following conditions: Neuroblastoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04106219?

The interventions under investigation include: Cyclophosphamide (DRUG), Topotecan (DRUG), LY3295668 Erbumine (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04106219?

This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04106219 being conducted?

This trial has 17 study locations across California, Colorado, Illinois, Massachusetts, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial