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NCT04051463 · ClinicalTrials.gov registry record · Phase 2

Rhopressa for Corneal Edema Associated With Fuchs Dystrophy

A Phase 2 study, sponsored by Price Vision Group.

Completed
Registry status
Phase 2
Development phase
29
Enrollment target

NCT04051463: Completed Phase 2 study, sponsored by Price Vision Group.

NCT04051463 is a Phase 2 study that has completed, run by Price Vision Group. The registered enrollment target is 29 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04051463, a Phase 2 study, has completed, sponsored by Price Vision Group.

COMPLETED
Registry status
Phase 2
Development phase
29 participants
Enrollment target

Study Summary

The study objective is to determine whether use of Rhopressa improves the ability of corneal endothelial cells to maintain appropriate corneal hydration in patients with Fuchs endothelial corneal dystrophy (FECD), which could help delay or prevent the need for a corneal transplant.

Primary Outcome

Central corneal thickness at 1 month after randomization minus central corneal thickness at baseline

Interventions

  • DRUG Placebo
  • DRUG Netarsudil Ophthalmic Solution

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2019-08-05
Est. Completion 2020-07-01
Phase Phase 2
Price Vision Group

10 total trials

What the finished NCT04051463 record still lists

NCT04051463 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04051463 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04051463 about?

NCT04051463 is a clinical study titled "Rhopressa for Corneal Edema Associated With Fuchs Dystrophy". The study objective is to determine whether use of Rhopressa improves the ability of corneal endothelial cells to maintain appropriate corneal hydration in patients with Fuchs endothelial corneal dystrophy (FECD), which could help delay or prevent the need for a corneal transplant.

What is the current status of trial NCT04051463?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2019-08-05. Estimated completion is 2020-07-01.

What interventions are being tested in trial NCT04051463?

The interventions under investigation include: Placebo (DRUG), Netarsudil Ophthalmic Solution (DRUG).

Who is sponsoring clinical trial NCT04051463?

This trial is sponsored by Price Vision Group, which has 10 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04051463's enrollment target sits among peer trials

29 1669th of 2000 higher than 324 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04051463, the US trial registry maintained by the National Library of Medicine. NCT04051463 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.