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NCT04039230 · ClinicalTrials.gov registry record · Phase 1

Study to Evaluate Sacituzumab Govitecan in Combination With Talazoparib in Patients With Metastatic Breast Cancer.

A Phase 1 study of Breast Cancer, sponsored by Massachusetts General Hospital.

Active
Registry status
Phase 1
Development phase
75
Enrollment target
3
Study locations

NCT04039230: Active Phase 1 study of Breast Cancer, sponsored by Massachusetts General Hospital.

NCT04039230 is a Phase 1 study of Breast Cancer that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 75 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (97% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04039230, a Phase 1 study of Breast Cancer, is active but no longer recruiting, sponsored by Massachusetts General Hospital.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
75 participants
Enrollment target
3
Study locations

Study Summary

This research is studying the effect of Antibody-Drug Conjugate Sacituzumab Govitecan in Combination with the Poly (Adenosine Diphosphate \[ADP\]-Ribose) Polymerase (PARP) Inhibitor Talazoparib in Patients with Metastatic Triple-Negative Breast Cancer.

Conditions Studied

Breast Cancer

Interventions

  • DRUG Sacituzumab Govitecan
  • DRUG Talazoparib

Study Locations (3)

Massachusetts

  • Massachusetts General Hospital Cancer Center - Boston
  • Boston Medical Center - Boston
  • Dana Farber Cancer Institute - Boston

Trial Details

FieldValue
Enrollment Target 75 participants
Start Date 2019-10-09
Est. Completion 2026-12
Phase Phase 1

Sponsor

Massachusetts General Hospital

2,032 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04039230

The ClinicalTrials.gov registry entry for NCT04039230 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 75 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (97% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Sacituzumab Govitecan is the first listed.

NCT04039230 reports 3 study locations spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04039230 about?

NCT04039230 is a clinical study titled "Study to Evaluate Sacituzumab Govitecan in Combination With Talazoparib in Patients With Metastatic Breast Cancer.". This research is studying the effect of Antibody-Drug Conjugate Sacituzumab Govitecan in Combination with the Poly (Adenosine Diphosphate \[ADP\]-Ribose) Polymerase (PARP) Inhibitor Talazoparib in Patients with Metastatic Triple-Negative Breast Cancer.

What is the current status of trial NCT04039230?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 75 participants. The study started on 2019-10-09. Estimated completion is 2026-12.

What conditions does trial NCT04039230 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT04039230?

The interventions under investigation include: Sacituzumab Govitecan (DRUG), Talazoparib (DRUG).

Who is sponsoring clinical trial NCT04039230?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04039230 being conducted?

This trial has 3 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.