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NCT04018274 · ClinicalTrials.gov registry record · Phase 1
Effect of PF-06651600 on the Pharmacokinetics of Oral Contraceptive Steroids
A Phase 1 study, sponsored by Pfizer.
- Completed
- Registry status
- Phase 1
- Development phase
- 29
- Enrollment target
NCT04018274: Completed Phase 1 study, sponsored by Pfizer.
NCT04018274 is a Phase 1 study that has completed, run by Pfizer. The registered enrollment target is 29 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (52% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04018274, a Phase 1 study, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 29 participants
- Enrollment target
Study Summary
This is a Phase 1, randomized, 2 way crossover, open-label study of the effect of multiple-dose PF 06651600 on single-dose oral contraceptive (OC) pharmacokinetics (PK) in healthy female subjects. Subjects will be randomized to 1 of 2 treatment sequences. A total of 28 healthy female subjects (14 in each treatment sequence) will be enrolled in the study. Each treatment sequence will consist of 2 periods.
Primary Outcome
30 micrograms administered as oral OC combination tablet
Interventions
- DRUG PF-06651600
- DRUG Ethinyl estradiol (EE) and levonorgestrel(LN)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2019-08-09 |
| Est. Completion | 2019-10-16 |
| Phase | Phase 1 |
What the finished NCT04018274 record still lists
NCT04018274 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (52% lower).
The record links to 0 conditions, and to 2 interventions - of which PF-06651600 is the first listed.
NCT04018274 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04018274 about?
NCT04018274 is a clinical study titled "Effect of PF-06651600 on the Pharmacokinetics of Oral Contraceptive Steroids". This is a Phase 1, randomized, 2 way crossover, open-label study of the effect of multiple-dose PF 06651600 on single-dose oral contraceptive (OC) pharmacokinetics (PK) in healthy female subjects. Subjects will be randomized to 1 of 2 treatment sequences. A total of 28 healthy female subjects (14 in...
What is the current status of trial NCT04018274?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 29 participants. The study started on 2019-08-09. Estimated completion is 2019-10-16.
What interventions are being tested in trial NCT04018274?
The interventions under investigation include: PF-06651600 (DRUG), Ethinyl estradiol (EE) and levonorgestrel(LN) (DRUG).
Who is sponsoring clinical trial NCT04018274?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04018274's enrollment target sits among peer trials
29 1440th of 2000 higher than 554 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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