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NCT03996018 · ClinicalTrials.gov registry record
T-cell Responses to Concurrent HIV and Herpesvirus Infections
A clinical trial, sponsored by St. Jude Children's Research Hospital.
- Completed
- Registry status
- 135
- Enrollment target
NCT03996018: Completed study, sponsored by St. Jude Children's Research Hospital.
NCT03996018 is a clinical trial that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 135 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03996018 has completed, sponsored by St. Jude Children's Research Hospital.
- COMPLETED
- Registry status
- 135 participants
- Enrollment target
Study Summary
This is a research study in which we are trying to discover new information about how HIV and herpes viruses interact with the immune system. The goal of the study is to learn more about how T-cells in your immune system respond to and fight off long-term (chronic) viruses, in order to improve medical care in the future.
Primary Outcome
using separated PBMCs, HIV-1 specific T-cells will be labeled with major histocompatibility complex (MHC) I tetramers previously described to be specific for HIV-1 \[14-18\]. Labeled cells will be subjected to flow cytometry for identity confirmation via established antibody cell marker staining, counting and sorting into single cells. The TCR genes of the individually sorted HIV-1 tetramer positive T-cells will then be sequenced, establishing a repertoire of TCR sequences. Diversities of the TC
Interventions
- OTHER T-cell lymphocyte responses
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 135 participants |
| Start Date | 2019-06-19 |
| Est. Completion | 2023-07-28 |
What the finished NCT03996018 record still lists
NCT03996018 is an observational study that tracks outcomes without assigning an intervention. The registered 135 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which T-cell lymphocyte responses is the first listed.
NCT03996018 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03996018 about?
NCT03996018 is a clinical study titled "T-cell Responses to Concurrent HIV and Herpesvirus Infections". This is a research study in which we are trying to discover new information about how HIV and herpes viruses interact with the immune system. The goal of the study is to learn more about how T-cells in your immune system respond to and fight off long-term (chronic) viruses, in order to improve medic...
What is the current status of trial NCT03996018?
This trial is currently completed. The enrollment target is 135 participants. The study started on 2019-06-19. Estimated completion is 2023-07-28.
What interventions are being tested in trial NCT03996018?
The interventions under investigation include: T-cell lymphocyte responses (OTHER).
Who is sponsoring clinical trial NCT03996018?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
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