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NCT03993171 · ClinicalTrials.gov registry record · Phase 2

31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis.

A Phase 2 study of Multiple Sclerosis, sponsored by Clene Nanomedicine.

Completed
Registry status
Phase 2
Development phase
33
Enrollment target
1
Study location

NCT03993171 is a Phase 2 study of Multiple Sclerosis that has completed, run by Clene Nanomedicine. The registered enrollment target is 33 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03993171, a Phase 2 study of Multiple Sclerosis, has completed, sponsored by Clene Nanomedicine.

COMPLETED
Registry status
Phase 2
Development phase
33 participants
Enrollment target
1
Study location

Study Summary

REPAIR-MS is a single-center open label, sequential group, investigator and patient blinded study to assess the CNS metabolic effects, safety, pharmacokinetics, and pharmacodynamics of CNM-Au8 in patients who have been diagnosed with Multiple Sclerosis (MS) within fifteen (15) years of Screening. The primary endpoint for this study changes from baseline to week 12 in CNS metabolic changes, based on 31P-MRSimaging.

Conditions Studied

Multiple Sclerosis

Interventions

  • DRUG gold nanocrystals

Study Locations (1)

Texas

  • University of Texas Southwestern - Dallas

Trial Details

FieldValue
Enrollment Target 33 participants
Start Date 2019-12-19
Est. Completion 2025-07-31
Phase Phase 2

Sponsor

Clene Nanomedicine

3 total trials

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What the Registry Record Tells You About NCT03993171

The ClinicalTrials.gov registry entry for NCT03993171 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 33 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (94% lower). The listed sponsor is Clene Nanomedicine, which has 3 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 1 intervention - of which gold nanocrystals is the first listed.

NCT03993171 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT03993171 about?

NCT03993171 is a clinical study titled "31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis.". REPAIR-MS is a single-center open label, sequential group, investigator and patient blinded study to assess the CNS metabolic effects, safety, pharmacokinetics, and pharmacodynamics of CNM-Au8 in patients who have been diagnosed with Multiple Sclerosis (MS) within fifteen (15) years of Screening. Th...

What is the current status of trial NCT03993171?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 33 participants. The study started on 2019-12-19. Estimated completion is 2025-07-31.

What conditions does trial NCT03993171 study?

This clinical trial studies the following conditions: Multiple Sclerosis.

What interventions are being tested in trial NCT03993171?

The interventions under investigation include: gold nanocrystals (DRUG).

Who is sponsoring clinical trial NCT03993171?

This trial is sponsored by Clene Nanomedicine, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03993171 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.