Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03988166 · ClinicalTrials.gov registry record · NA
Chronic Total Occlusion Percutaneous Coronary Intervention Study
A NA study of Ischemic Heart Disease and Chronic Total Occlusion of Coronary Artery, sponsored by Vascular Solutions.
- Completed
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 13
- Study locations
NCT03988166: Completed NA study of Ischemic Heart Disease and Chronic Total Occlusion of Coronary Artery, sponsored by Vascular Solutions.
NCT03988166 is a NA study of Ischemic Heart Disease and Chronic Total Occlusion of Coronary Artery that has completed, run by Vascular Solutions. The registered enrollment target is 150 participants, below the 256-participant average among 14 other Ischemic Heart Disease trials with a reported enrollment target (41% lower). The trial reports 13 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03988166, a NA study of Ischemic Heart Disease and Chronic Total Occlusion of Coronary Artery, has completed, sponsored by Vascular Solutions.
- COMPLETED
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 13
- Study locations
Study Summary
The objective of this study is to evaluate angiographic confirmation of placement of any guidewire beyond the CTO, in the true vessel lumen, in patients undergoing CTO percutaneous coronary intervention (PCI) in which at least one Teleflex guidewire and at least one Turnpike catheter are used.
Primary Outcome
Defined as angiographic visualization of any guidewire in a position either distal or proximal to the occlusion depending on the route of access and the absence of in-hospital major adverse cardiac events (MACE). • MACE defined as any serious adverse experience that includes cardiac death, target lesion revascularization, or post-procedural myocardial infarction (MI) (Q-wave or non-Q-wave, with creatine kinase (CK) with Muscle (M)-Brain (B) subunits \> 3 ULN).
Conditions Studied
Interventions
- PROCEDURE Chronic Total Occlusion Revascularization
- DEVICE GuideLiner® V3 catheter, TrapLiner® catheter, Turnpike® catheter
Study Locations (13)
Massachusetts
- Brigham and Women's Hospital - Boston
- Massachusetts General Hospital - Boston
- Beth Israel Deaconess Medical Center - Boston
Georgia
- Piedmont Heart Institute - Atlanta
- Emory University - Atlanta
New York
- NYU Langone Health - New York
- Columbia University Medical Center - New York
California
- Torrance Memorial Medical Center - Torrance
Michigan
- Henry Ford Hospital - Detroit
Minnesota
- Minneapolis Heart Institute Foundation - Minneapolis
Missouri
- Missouri Cardiovascular Specialists - Columbia
Ohio
- The Christ Hospital - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2020-05-20 |
| Est. Completion | 2021-02-22 |
| Phase | NA |
What the finished NCT03988166 record still lists
NCT03988166 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 256-participant average among 14 other Ischemic Heart Disease trials with a reported enrollment target (41% lower).
The record links to 3 conditions, with Ischemic Heart Disease appearing as the primary indexed condition, and to 2 interventions - of which Chronic Total Occlusion Revascularization is the first listed.
NCT03988166 lists 13 locations in 9 states (Massachusetts, Georgia, New York).
Frequently Asked Questions
What is clinical trial NCT03988166 about?
NCT03988166 is a clinical study titled "Chronic Total Occlusion Percutaneous Coronary Intervention Study". The objective of this study is to evaluate angiographic confirmation of placement of any guidewire beyond the CTO, in the true vessel lumen, in patients undergoing CTO percutaneous coronary intervention (PCI) in which at least one Teleflex guidewire and at least one Turnpike catheter are used.
What is the current status of trial NCT03988166?
This trial is currently completed. It is a NA study. The enrollment target is 150 participants. The study started on 2020-05-20. Estimated completion is 2021-02-22.
What conditions does trial NCT03988166 study?
This clinical trial studies the following conditions: Ischemic Heart Disease, Chronic Total Occlusion of Coronary Artery, Chronic Total Occlusion.
What interventions are being tested in trial NCT03988166?
The interventions under investigation include: Chronic Total Occlusion Revascularization (PROCEDURE), GuideLiner® V3 catheter, TrapLiner® catheter, Turnpike® catheter (DEVICE).
Who is sponsoring clinical trial NCT03988166?
This trial is sponsored by Vascular Solutions, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03988166 being conducted?
This trial has 13 study locations across California, Georgia, Massachusetts, Michigan, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Ischemic Heart Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03988166's enrollment target sits among peer trials
150 5th of 14 higher than 9 of 14 other Ischemic Heart Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ischemic Heart Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Pulsed Field Ablation for Post-Infarction Ventricular Tachycardia
RECRUITING · NA
-
Use of GeriKit to Better Phenotype Older Adults With Ischemic Heart Disease
RECRUITING · NA
-
A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction
ACTIVE NOT RECRUITING · NA
-
AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
RECRUITING
-
Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
RECRUITING
-
Single or Repeated Intravenous Administration of umbiliCAl Cord Mesenchymal sTrOmal Cells in Ischemic Cardiomyopathy
RECRUITING · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00412594 · 150 participants · Phase 2
Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia
- NCT01484730 · 150 participants
A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion
- NCT01985919 · 150 participants
Protocol for Facilitating the Acquisition of Research Bone Marrow and Blood Samples
- NCT02016248 · 150 participants · NA
SBRT Boost for Unfavorable Prostate Cancer'
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI