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NCT06891456 · ClinicalTrials.gov registry record · NA

Pulsed Field Ablation for Post-Infarction Ventricular Tachycardia

A NA study of Ventricular Tachycardia and Ischemic Heart Disease, sponsored by Pasquale Santangeli.

Recruiting
Registry status
NA
Development phase
40
Enrollment target
1
Study location

NCT06891456 is a NA study of Ventricular Tachycardia and Ischemic Heart Disease that is actively recruiting participants, run by Pasquale Santangeli. The registered enrollment target is 40 participants, below the 287-participant average among 28 other Ventricular Tachycardia trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06891456, a NA study of Ventricular Tachycardia and Ischemic Heart Disease, is actively recruiting participants, sponsored by Pasquale Santangeli.

RECRUITING
Registry status
NA
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

ASCEND is a randomized controlled open-label pilot study evaluating the safety and effectiveness of pulsed field ablation (PFA) with the novel FARAPOINT catheter compared to the standard radiofrequency (RFA) ablation with ThermoCool ST/FlexAbility SE/ThermoCool ST SF/TactiFlex SE of ventricular tachycardia (VT) in the patients with ischemic cardiomyopathy and implantable cardioverter-defibrillator (ICD). The study hypothesis is that the PFA ablation is more efficient compared to the RFA technique but retains a comparable safety profile.

Conditions Studied

Ventricular Tachycardia Ischemic Heart Disease Sustained VT

Interventions

  • DEVICE RFA Ablation
  • DEVICE PFA Ablation

Study Locations (1)

Ohio

  • Cleveland Clinic - Cleveland

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2025-06-16
Est. Completion 2028-12-31
Phase NA

Sponsor

Pasquale Santangeli

1 total trials

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What the Registry Record Tells You About NCT06891456

The ClinicalTrials.gov registry entry for NCT06891456 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 287-participant average among 28 other Ventricular Tachycardia trials with a reported enrollment target (86% lower). The listed sponsor is Pasquale Santangeli, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Ventricular Tachycardia appearing as the primary indexed condition, and to 2 interventions - of which RFA Ablation is the first listed.

NCT06891456 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT06891456 about?

NCT06891456 is a clinical study titled "Pulsed Field Ablation for Post-Infarction Ventricular Tachycardia". ASCEND is a randomized controlled open-label pilot study evaluating the safety and effectiveness of pulsed field ablation (PFA) with the novel FARAPOINT catheter compared to the standard radiofrequency (RFA) ablation with ThermoCool ST/FlexAbility SE/ThermoCool ST SF/TactiFlex SE of ventricular tach...

What is the current status of trial NCT06891456?

This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-06-16. Estimated completion is 2028-12-31.

What conditions does trial NCT06891456 study?

This clinical trial studies the following conditions: Ventricular Tachycardia, Ischemic Heart Disease, Sustained VT.

What interventions are being tested in trial NCT06891456?

The interventions under investigation include: RFA Ablation (DEVICE), PFA Ablation (DEVICE).

Who is sponsoring clinical trial NCT06891456?

This trial is sponsored by Pasquale Santangeli, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06891456 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.