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NCT03968874 · ClinicalTrials.gov registry record · NA
Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans
A NA study of Traumatic Brain Injury, sponsored by Portland VA Medical Center.
- Active
- Registry status
- NA
- Development phase
- 300
- Enrollment target
- 1
- Study location
NCT03968874: Active NA study of Traumatic Brain Injury, sponsored by Portland VA Medical Center.
NCT03968874 is a NA study of Traumatic Brain Injury that is active but no longer recruiting, run by Portland VA Medical Center. The registered enrollment target is 300 participants, roughly in line with the 276-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03968874, a NA study of Traumatic Brain Injury, is active but no longer recruiting, sponsored by Portland VA Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary purpose of this project is to determine the effect of morning bright light therapy (MBLT) on sleep in Veterans with traumatic brain injury (TBI). Secondarily, the project aims to identify blood-based brain biomarkers (BBBM) associated with sleep in Veterans. Specific Aim 1. Determine the effect of MBLT on sleep quality in Veterans (primary outcome). Specific Aim 2. Determine the effect of MBLT on downstream effectors of improved sleep, including cognition, mood, and quality of life measures in Veterans (exploratory outcomes). Specific Aim 3. Determine the effect of MBLT on levels of specific BBBM related to sleep, and whether changes in specific BBBM predict response to MBLT (secondary outcome). This study can now be completed 100% remotely.
Primary Outcome
Measures self-reported insomnia severity; total score range = 0-28 (higher total score = worse insomnia)
Conditions Studied
Interventions
- DEVICE Negative Ion Generator
- DEVICE Light box therapy
Study Locations (1)
Oregon
- Portland VA Medical Center - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2019-08-01 |
| Est. Completion | 2025-12-01 |
| Phase | NA |
What the registry record for NCT03968874 still lists
NCT03968874 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 276-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target.
The record links to 1 condition, with Traumatic Brain Injury appearing as the primary indexed condition, and to 2 interventions - of which Negative Ion Generator is the first listed.
NCT03968874 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT03968874 about?
NCT03968874 is a clinical study titled "Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans". The primary purpose of this project is to determine the effect of morning bright light therapy (MBLT) on sleep in Veterans with traumatic brain injury (TBI). Secondarily, the project aims to identify blood-based brain biomarkers (BBBM) associated with sleep in Veterans. Specific Aim 1. Determine th...
What is the current status of trial NCT03968874?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 300 participants. The study started on 2019-08-01. Estimated completion is 2025-12-01.
What conditions does trial NCT03968874 study?
This clinical trial studies the following conditions: Traumatic Brain Injury.
What interventions are being tested in trial NCT03968874?
The interventions under investigation include: Negative Ion Generator (DEVICE), Light box therapy (DEVICE).
Who is sponsoring clinical trial NCT03968874?
This trial is sponsored by Portland VA Medical Center, which has 15 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03968874 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Traumatic Brain Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03968874's enrollment target sits among peer trials
300 20th of 171 higher than 146 of 171 other Traumatic Brain Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Traumatic Brain Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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