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NCT03947684 · ClinicalTrials.gov registry record
Exploring the Modulatory Role of Sex Hormones Along the Neuromechanical Axis in Females
A clinical trial of Role of Sex Hormones Along the Neuromechanical Axis, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- 102
- Enrollment target
- 1
- Study location
NCT03947684 is a study of Role of Sex Hormones Along the Neuromechanical Axis that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 102 participants. The trial reports 1 study location across 1 state.
The verdict
NCT03947684, a study of Role of Sex Hormones Along the Neuromechanical Axis, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- 102 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this project is to test our central hypothesis that changes in sex hormone concentration result in changes to the basic elements of motor control - at multiple levels, from the musculotendinous unit to motor control circuitry. Under Aim 1 the investigator will determine the influence of sex hormone fluctuations on the muscle stretch reflex during active and passive states, and the time lag between hormone concentration changes and the reflex response. The investigator will use a technically simple assessment that could be implemented in the field. Under Aim 2 the investigator will determine the influence of sex hormone fluctuations on spinal motor neuron excitability using H-reflex as a probe and the simultaneous change in the muscle mechanics using muscle twitch response. Aims 1 \& 2 will include a focus on the differential role of oral contraceptives. In Aim 3 the investigator will use paired-pulse transcranial magnetic stimulation during active contraction to determine the influence of sex hormone fluctuation.
Conditions Studied
Study Locations (1)
Texas
- UT Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 102 participants |
| Start Date | 2019-04-12 |
| Est. Completion | 2024-04-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03947684
The ClinicalTrials.gov registry entry for NCT03947684 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 102 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Role of Sex Hormones Along the Neuromechanical Axis appearing as the primary indexed condition, and to 0 interventions.
NCT03947684 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT03947684 about?
NCT03947684 is a clinical study titled "Exploring the Modulatory Role of Sex Hormones Along the Neuromechanical Axis in Females". The goal of this project is to test our central hypothesis that changes in sex hormone concentration result in changes to the basic elements of motor control - at multiple levels, from the musculotendinous unit to motor control circuitry. Under Aim 1 the investigator will determine the influence of ...
What is the current status of trial NCT03947684?
This trial is currently completed. The enrollment target is 102 participants. The study started on 2019-04-12. Estimated completion is 2024-04-30.
What conditions does trial NCT03947684 study?
This clinical trial studies the following conditions: Role of Sex Hormones Along the Neuromechanical Axis.
Who is sponsoring clinical trial NCT03947684?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03947684 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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