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NCT03838874 · ClinicalTrials.gov registry record · Phase 2
Mepivacaine Versus Low-Dose Bupivacaine For Primary Total Hip and Knee Arthroplasty
A Phase 2 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 2
- Development phase
- 154
- Enrollment target
NCT03838874: Completed Phase 2 study, sponsored by Mayo Clinic.
NCT03838874 is a Phase 2 study that has completed, run by Mayo Clinic. The registered enrollment target is 154 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (16% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03838874, a Phase 2 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 154 participants
- Enrollment target
Study Summary
This research is being done to see if there is a difference between two different spinal anesthetics (Mepivacaine vs. Bupivacaine) as it relates to reducing post-operative complications and the time it takes for subjects to regain mobility after surgery.
Primary Outcome
Assessed by measuring time from spinal anesthetic administration to postoperative achievement of Bromage 0 function (return of spontaneous ankle, knee, and hip movement) in the non-operative extremity at 15-minute intervals.
Interventions
- DRUG Mepivacaine
- DRUG Low-Dose Bupivacaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 154 participants |
| Start Date | 2019-02-25 |
| Est. Completion | 2019-10-29 |
| Phase | Phase 2 |
What the finished NCT03838874 record still lists
NCT03838874 is an interventional study that assigns participants to a tested intervention. The registered 154 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (16% higher).
The record links to 0 conditions, and to 2 interventions - of which Mepivacaine is the first listed.
NCT03838874 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03838874 about?
NCT03838874 is a clinical study titled "Mepivacaine Versus Low-Dose Bupivacaine For Primary Total Hip and Knee Arthroplasty". This research is being done to see if there is a difference between two different spinal anesthetics (Mepivacaine vs. Bupivacaine) as it relates to reducing post-operative complications and the time it takes for subjects to regain mobility after surgery.
What is the current status of trial NCT03838874?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 154 participants. The study started on 2019-02-25. Estimated completion is 2019-10-29.
What interventions are being tested in trial NCT03838874?
The interventions under investigation include: Mepivacaine (DRUG), Low-Dose Bupivacaine (DRUG).
Who is sponsoring clinical trial NCT03838874?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03838874's enrollment target sits among peer trials
154 448th of 2000 higher than 1,552 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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