Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 2

A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery

NCT03809000 · View on ClinicalTrials.gov ↗

Study Summary

Patients with post-prostatectomy PSA (Prostate Specific Antigen) recurrences with aggressive disease features will receive salvage radiation therapy and standard androgen deprivation therapy (ADT) or enhanced ADT to determine if there is any improvement in progression-free survival when enhanced ADT is used compared to standard ADT.

Conditions Studied

Interventions

  • RADIATION Radiation Therapy
  • DRUG Enzalutamide
  • DRUG Bicalutamide
  • DRUG GnRH analog

Study Locations (20)

California

  • Marin Cancer Care, Inc. — Greenbrae
  • Marin Health Medical Center — Greenbrae
  • University of Southern California — Los Angeles
  • USC Medical Center - Los Angeles County — Los Angeles
  • Cedars-Sinai Medical Center — Los Angeles
  • Roseville Radiation Oncology Center — Roseville
  • Sutter Roseville Medical Center — Roseville
  • Sutter Medical Center Sacramento — Sacramento
  • University of California, San Francisco — San Francisco

Arizona

  • Arizona Center for Cancer Care - Gilbert — Gilbert
  • Arizona Center for Cancer Care - Peoria — Peoria
  • Arizona Center for Cancer Care - Phoenix — Phoenix
  • Arizona Center for Cancer Care - Scottsdale East — Scottsdale
  • Arizona Center for Cancer Care - Scottsdale North — Scottsdale
  • Arizona Center for Cancer Care - Surprise — Surprise

Florida

  • University of Florida Health Science Center — Gainesville
  • AdventHealth Orlando — Orlando
  • Moffitt Cancer Center — Tampa

Colorado

  • Valley View Hospital Cancer Center — Glenwood Springs

Georgia

  • Nancy N. & J.C. Lewis Cancer & Research Pavilion — Savannah

Trial Details

FieldValue
Enrollment Target 188 participants
Start Date 2019-04-15
Est. Completion 2029-09-15
Phase Phase 2

Sponsor

RTOG Foundation

3 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03809000

The ClinicalTrials.gov registry entry for NCT03809000 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 188 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is RTOG Foundation, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 4 interventions — of which Radiation Therapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03809000 reports 20 study locations spanning 5 distinct geographic areas — top geographies include California, Arizona, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03809000 about?

NCT03809000 is a clinical study titled "A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery". Patients with post-prostatectomy PSA (Prostate Specific Antigen) recurrences with aggressive disease features will receive salvage radiation therapy and standard androgen deprivation therapy (ADT) or enhanced ADT to determine if there is any improvement in progression-free survival when enhanced ADT...

What is the current status of trial NCT03809000?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 188 participants. The study started on 2019-04-15. Estimated completion is 2029-09-15.

What conditions does trial NCT03809000 study?

This clinical trial studies the following conditions: Prostate Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03809000?

The interventions under investigation include: Radiation Therapy (RADIATION), Enzalutamide (DRUG), Bicalutamide (DRUG), GnRH analog (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03809000?

This trial is sponsored by RTOG Foundation, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03809000 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial