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NCT03803553 · ClinicalTrials.gov registry record · Phase 3

Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer

A Phase 3 study of Stage III Colon Cancer and Metastatic Colon Cancer, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
Phase 3
Development phase
400
Enrollment target
3
Study locations

NCT03803553 is a Phase 3 study of Stage III Colon Cancer and Metastatic Colon Cancer that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 400 participants, below the 750-participant average among 6 other Stage III Colon Cancer trials with a reported enrollment target (47% lower). The trial reports 3 study locations across 2 states.

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The verdict

NCT03803553, a Phase 3 study of Stage III Colon Cancer and Metastatic Colon Cancer, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
Phase 3
Development phase
400 participants
Enrollment target
3
Study locations

Study Summary

This research study is comparing two standard of care treatment options based on blood test results for participants who have metastatic colon cancer. The names of the potential treatments involved in this study are: * Active surveillance * FOLFIRI treatment * Nivolumab treatment * Encorafenib/Binimetinib/Cetuximab treatment * Trastuzumab + Pertuzumab

Interventions

  • DRUG FOLFIRI Protocol
  • OTHER ACTIVE SURVEILLANCE
  • DRUG Nivolumab Protocol
  • DRUG Encorafenib/Binimetinib/Cetuximab Protocol
  • DRUG Trastuzumab + Pertuzumab

Study Locations (3)

New York

  • Memorial Sloan Kettering Cancer Center - New York
  • Weill Cornell Medical College - New York

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2020-04-16
Est. Completion 2027-12
Phase Phase 3

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT03803553

The ClinicalTrials.gov registry entry for NCT03803553 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 750-participant average among 6 other Stage III Colon Cancer trials with a reported enrollment target (47% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Stage III Colon Cancer appearing as the primary indexed condition, and to 5 interventions - of which FOLFIRI Protocol is the first listed.

NCT03803553 reports 3 study locations spanning 2 distinct geographic areas - top geographies include New York, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT03803553 about?

NCT03803553 is a clinical study titled "Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer". This research study is comparing two standard of care treatment options based on blood test results for participants who have metastatic colon cancer. The names of the potential treatments involved in this study are: * Active surveillance * FOLFIRI treatment * Nivolumab treatment * Encorafenib/Bin...

What is the current status of trial NCT03803553?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 400 participants. The study started on 2020-04-16. Estimated completion is 2027-12.

What conditions does trial NCT03803553 study?

This clinical trial studies the following conditions: Stage III Colon Cancer, Metastatic Colon Cancer.

What interventions are being tested in trial NCT03803553?

The interventions under investigation include: FOLFIRI Protocol (DRUG), ACTIVE SURVEILLANCE (OTHER), Nivolumab Protocol (DRUG), Encorafenib/Binimetinib/Cetuximab Protocol (DRUG), Trastuzumab + Pertuzumab (DRUG).

Who is sponsoring clinical trial NCT03803553?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03803553 being conducted?

This trial has 3 study locations across Massachusetts, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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