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NCT00004931 · ClinicalTrials.gov registry record · Phase 3
Fluorouracil Plus Leucovorin With or Without Oxaliplatin in Treating Patients With Stage II or Stage III Colon Cancer
A Phase 3 study of Stage III Colon Cancer and Stage II Colon Cancer, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 3
- Development phase
- 2,472
- Enrollment target
- 1
- Study location
NCT00004931 is a Phase 3 study of Stage III Colon Cancer and Stage II Colon Cancer that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 2,472 participants, above the 404-participant average among 6 other Stage III Colon Cancer trials with a reported enrollment target (512% higher). The trial reports 1 study location across 1 state.
The verdict
NCT00004931, a Phase 3 study of Stage III Colon Cancer and Stage II Colon Cancer, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 2,472 participants
- Enrollment target
- 1
- Study location
Study Summary
Randomized phase III trial to compare the effectiveness of fluorouracil plus leucovorin with or without oxaliplatin in treating patients who have stage II or stage III colon cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more effective for colon cancer
Conditions Studied
Interventions
- OTHER laboratory biomarker analysis
- DRUG oxaliplatin
- DRUG fluorouracil
- DRUG leucovorin calcium
Study Locations (1)
Pennsylvania
- National Surgical Adjuvant Breast and Bowel Project - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,472 participants |
| Start Date | 2000-02 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00004931
The ClinicalTrials.gov registry entry for NCT00004931 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 2,472 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 404-participant average among 6 other Stage III Colon Cancer trials with a reported enrollment target (512% higher). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Stage III Colon Cancer appearing as the primary indexed condition, and to 4 interventions - of which laboratory biomarker analysis is the first listed.
NCT00004931 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00004931 about?
NCT00004931 is a clinical study titled "Fluorouracil Plus Leucovorin With or Without Oxaliplatin in Treating Patients With Stage II or Stage III Colon Cancer". Randomized phase III trial to compare the effectiveness of fluorouracil plus leucovorin with or without oxaliplatin in treating patients who have stage II or stage III colon cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining...
What is the current status of trial NCT00004931?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 2,472 participants. The study started on 2000-02.
What conditions does trial NCT00004931 study?
This clinical trial studies the following conditions: Stage III Colon Cancer, Stage II Colon Cancer.
What interventions are being tested in trial NCT00004931?
The interventions under investigation include: laboratory biomarker analysis (OTHER), oxaliplatin (DRUG), fluorouracil (DRUG), leucovorin calcium (DRUG).
Who is sponsoring clinical trial NCT00004931?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00004931 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.