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NCT03718936 · ClinicalTrials.gov registry record
ADNP Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing ADNP-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.
A clinical trial of Autism Spectrum Disorder and ADNP, sponsored by Icahn School of Medicine at Mount Sinai.
- Recruiting
- Registry status
- 30
- Enrollment target
- 1
- Study location
NCT03718936: Recruiting study of Autism Spectrum Disorder and ADNP, sponsored by Icahn School of Medicine at Mount Sinai.
NCT03718936 is a study of Autism Spectrum Disorder and ADNP that is actively recruiting participants, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 30 participants, below the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03718936, a study of Autism Spectrum Disorder and ADNP, is actively recruiting participants, sponsored by Icahn School of Medicine at Mount Sinai.
- RECRUITING
- Registry status
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
ADNP, also known as Activity Dependent Neuroprotective Protein, is a rare neurodevelopmental disorder caused by mutations encompassing the ADNP gene on chromosome 20. Clinically, ADNP syndrome is characterized by intellectual disability and global developmental delay. This study seeks to characterize ADNP-related neurodevelopmental disorders using a number of genetic, medical and neuropsychological measures.
Primary Outcome
The ADOS is a structured, play-based assessment of communication, social interaction and behavior in individuals (children and adults) suspected of having a diagnosis of Autism Spectrum Disorder. The examiner will select 1 of 4 different ADOS modules, which differ based on chronological age and verbal fluency, to use for the individual being assessed. An Overall Total score \>= 16, if the individual meets for the "few to no words" algorithm, or 12, if the individual meets for the "some words" al
Conditions Studied
Study Locations (1)
New York
- The Seaver Autism Center for Research and Treatment - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2017-11-14 |
| Est. Completion | 2027-03 |
What NCT03718936 shows while recruiting
NCT03718936 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (78% lower).
The record links to 3 conditions, with Autism Spectrum Disorder appearing as the primary indexed condition, and to 0 interventions.
NCT03718936 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT03718936 about?
NCT03718936 is a clinical study titled "ADNP Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing ADNP-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.". ADNP, also known as Activity Dependent Neuroprotective Protein, is a rare neurodevelopmental disorder caused by mutations encompassing the ADNP gene on chromosome 20. Clinically, ADNP syndrome is characterized by intellectual disability and global developmental delay. This study seeks to characteriz...
What is the current status of trial NCT03718936?
This trial is currently recruiting. The enrollment target is 30 participants. The study started on 2017-11-14. Estimated completion is 2027-03.
What conditions does trial NCT03718936 study?
This clinical trial studies the following conditions: Autism Spectrum Disorder, ADNP, Helsmoortel-Van Der Aa Syndrome.
Who is sponsoring clinical trial NCT03718936?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03718936 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03718936's enrollment target sits among peer trials
30 170th of 224 higher than 50 of 224 other Autism Spectrum Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Autism Spectrum Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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