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NCT03714152 · ClinicalTrials.gov registry record · Phase 1
A Study of ABI-H2158 in Healthy Volunteers and Patients With Chronic Hepatitis B
A Phase 1 study, sponsored by Assembly Biosciences.
- Completed
- Registry status
- Phase 1
- Development phase
- 80
- Enrollment target
NCT03714152: Completed Phase 1 study, sponsored by Assembly Biosciences.
NCT03714152 is a Phase 1 study that has completed, run by Assembly Biosciences. The registered enrollment target is 80 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03714152, a Phase 1 study, has completed, sponsored by Assembly Biosciences.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 80 participants
- Enrollment target
Study Summary
This three-part, Phase 1 protocol will be the first clinical study of ABI-H2158. Parts 1 and 2 will be a Phase 1a, dose-ranging assessment of ABI-H2158 in healthy adult volunteers. If the dose-related safety, tolerability, and pharmacokinetics (PK) of ABI-H2158 in healthy volunteers are deemed satisfactory, then the study will advance to Part 3, a Phase 1b, dose-ranging assessment of ABI-H2158 in non-cirrhotic, CHB patients.
Interventions
- DRUG ABI-H2158
- DRUG Placebo for ABI-H2158
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2018-11-13 |
| Est. Completion | 2021-01-07 |
| Phase | Phase 1 |
What the finished NCT03714152 record still lists
NCT03714152 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher).
The record links to 0 conditions, and to 2 interventions - of which ABI-H2158 is the first listed.
NCT03714152 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03714152 about?
NCT03714152 is a clinical study titled "A Study of ABI-H2158 in Healthy Volunteers and Patients With Chronic Hepatitis B". This three-part, Phase 1 protocol will be the first clinical study of ABI-H2158. Parts 1 and 2 will be a Phase 1a, dose-ranging assessment of ABI-H2158 in healthy adult volunteers. If the dose-related safety, tolerability, and pharmacokinetics (PK) of ABI-H2158 in healthy volunteers are deemed satis...
What is the current status of trial NCT03714152?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2018-11-13. Estimated completion is 2021-01-07.
What interventions are being tested in trial NCT03714152?
The interventions under investigation include: ABI-H2158 (DRUG), Placebo for ABI-H2158 (DRUG).
Who is sponsoring clinical trial NCT03714152?
This trial is sponsored by Assembly Biosciences, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03714152's enrollment target sits among peer trials
80 672nd of 2000 higher than 1,305 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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