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NCT03662074 · ClinicalTrials.gov registry record · Phase 2

Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancer

A Phase 2 study, sponsored by Wake Forest University Health Sciences.

Terminated
Registry status
Phase 2
Development phase
14
Enrollment target

NCT03662074 is a Phase 2 study that was terminated before completion, run by Wake Forest University Health Sciences. The registered enrollment target is 14 participants.

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The verdict

NCT03662074, a Phase 2 study, was terminated before completion, sponsored by Wake Forest University Health Sciences.

TERMINATED
Registry status
Phase 2
Development phase
14 participants
Enrollment target

Study Summary

This phase II pilot trial studies how well gemcitabine and nivolumab work in treating participants with small cell lung cancer that has spread to other parts of the body after other treatments have failed. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Giving second-line gemcitabine and nivolumab may work better in treating participants with small cell lung cancer.

Interventions

  • DRUG Gemcitabine
  • BIOLOGICAL Nivolumab

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2018-11-07
Est. Completion 2022-02-03
Phase Phase 2

Sponsor

Wake Forest University Health Sciences

1,140 total trials

What the Registry Record Tells You About NCT03662074

The ClinicalTrials.gov registry entry for NCT03662074 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wake Forest University Health Sciences, which has 1,140 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Gemcitabine is the first listed.

NCT03662074 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03662074 about?

NCT03662074 is a clinical study titled "Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancer". This phase II pilot trial studies how well gemcitabine and nivolumab work in treating participants with small cell lung cancer that has spread to other parts of the body after other treatments have failed. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of ...

What is the current status of trial NCT03662074?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 14 participants. The study started on 2018-11-07. Estimated completion is 2022-02-03.

What interventions are being tested in trial NCT03662074?

The interventions under investigation include: Gemcitabine (DRUG), Nivolumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT03662074?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.