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NCT03658304 · ClinicalTrials.gov registry record · Phase 2
Trial of Mitomycin C During Nephroureterectomy for Urothelial Carcinoma
A Phase 2 study, sponsored by University of Florida.
- Completed
- Registry status
- Phase 2
- Development phase
- 29
- Enrollment target
NCT03658304: Completed Phase 2 study, sponsored by University of Florida.
NCT03658304 is a Phase 2 study that has completed, run by University of Florida. The registered enrollment target is 29 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03658304, a Phase 2 study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 29 participants
- Enrollment target
Study Summary
Results of previous studies suggest that the timing of intravesical mitomycin C administration may impact bladder tumor recurrence rate following radical nephroureterectomy. This is the first study of its kind to attempt to identify the importance of timing of mitomycin C administration relative to bladder tumor recurrence rate following radical nephroureterectomy.This study will investigate the one year bladder tumor recurrence rate in patients with urothelial carcinoma of the upper urinary tract following intraoperative administration of mitomycin C during a nephroureterectomy, as well as the time to bladder tumor recurrence in this patient population.
Primary Outcome
The bladder tumor recurrence rate will be measured by the percentage of subjects who are confirmed by bladder biopsy to have a recurrence of urothelial carcinoma in the bladder following nephroureterectomy
Interventions
- DRUG Mitomycin c
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2018-12-05 |
| Est. Completion | 2023-10-17 |
| Phase | Phase 2 |
What the finished NCT03658304 record still lists
NCT03658304 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% lower).
The record links to 0 conditions, and to 1 intervention - of which Mitomycin c is the first listed.
NCT03658304 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03658304 about?
NCT03658304 is a clinical study titled "Trial of Mitomycin C During Nephroureterectomy for Urothelial Carcinoma". Results of previous studies suggest that the timing of intravesical mitomycin C administration may impact bladder tumor recurrence rate following radical nephroureterectomy. This is the first study of its kind to attempt to identify the importance of timing of mitomycin C administration relative to ...
What is the current status of trial NCT03658304?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2018-12-05. Estimated completion is 2023-10-17.
What interventions are being tested in trial NCT03658304?
The interventions under investigation include: Mitomycin c (DRUG).
Who is sponsoring clinical trial NCT03658304?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03658304's enrollment target sits among peer trials
29 1669th of 2000 higher than 324 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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