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NCT03648385 · ClinicalTrials.gov registry record · Phase 2

Effects of DHEA in Pulmonary Hypertension

A Phase 2 study of Pulmonary Arterial Hypertension, sponsored by Rhode Island Hospital.

Completed
Registry status
Phase 2
Development phase
26
Enrollment target
1
Study location

NCT03648385 is a Phase 2 study of Pulmonary Arterial Hypertension that has completed, run by Rhode Island Hospital. The registered enrollment target is 26 participants, below the 462-participant average among 63 other Pulmonary Arterial Hypertension trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03648385, a Phase 2 study of Pulmonary Arterial Hypertension, has completed, sponsored by Rhode Island Hospital.

COMPLETED
Registry status
Phase 2
Development phase
26 participants
Enrollment target
1
Study location

Study Summary

The goal of this crossover trial is to determine whether the study drug dehydroepiandrosterone (DHEA) improves right ventricular longitudinal strain measured by cardiac magnetic resonance imaging at 18 weeks AND 40 weeks compared to placebo and to assess side effects and safety in pulmonary arterial hypertension.

Interventions

  • OTHER Placebo
  • DRUG DHEA tablet

Study Locations (1)

Rhode Island

  • Rhode Island Hospital Pulmonary Hypertension Center - Providence

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2019-01-09
Est. Completion 2024-12-30
Phase Phase 2

Sponsor

Rhode Island Hospital

130 total trials

What the Registry Record Tells You About NCT03648385

The ClinicalTrials.gov registry entry for NCT03648385 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 462-participant average among 63 other Pulmonary Arterial Hypertension trials with a reported enrollment target (94% lower). The listed sponsor is Rhode Island Hospital, which has 130 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pulmonary Arterial Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT03648385 reports 1 study location spanning 1 distinct geographic area - top geographies include Rhode Island.

Frequently Asked Questions

What is clinical trial NCT03648385 about?

NCT03648385 is a clinical study titled "Effects of DHEA in Pulmonary Hypertension". The goal of this crossover trial is to determine whether the study drug dehydroepiandrosterone (DHEA) improves right ventricular longitudinal strain measured by cardiac magnetic resonance imaging at 18 weeks AND 40 weeks compared to placebo and to assess side effects and safety in pulmonary arterial...

What is the current status of trial NCT03648385?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 26 participants. The study started on 2019-01-09. Estimated completion is 2024-12-30.

What conditions does trial NCT03648385 study?

This clinical trial studies the following conditions: Pulmonary Arterial Hypertension.

What interventions are being tested in trial NCT03648385?

The interventions under investigation include: Placebo (OTHER), DHEA tablet (DRUG).

Who is sponsoring clinical trial NCT03648385?

This trial is sponsored by Rhode Island Hospital, which has 130 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03648385 being conducted?

This trial has 1 study location across Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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