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NCT03646877 · ClinicalTrials.gov registry record · Phase 1
Mechanisms of Ozone-Induced Alterations in Efferocytosis and Phagocytosis
A Phase 1 study, sponsored by Robert Tighe, MD.
- Completed
- Registry status
- Phase 1
- Development phase
- 35
- Enrollment target
NCT03646877 is a Phase 1 study that has completed, run by Robert Tighe, MD. The registered enrollment target is 35 participants.
The verdict
NCT03646877, a Phase 1 study, has completed, sponsored by Robert Tighe, MD.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 35 participants
- Enrollment target
Study Summary
The purpose of this research study to understand how environmental and genetic factors may be involved in lung function. Healthy Study participants will undergo a 1-day screening that includes a blood draw and breathing testing, return for a two-day series of testing to include blood draw, and brief breathing test before and after an inhaled challenge with either filtered air (FA) or ozone (O3). Participants return the next day for a brief breathing test, a blood draw and a procedure called bronchoscopy performed under conscious sedation to evaluate the lung after the challenge. Participants then return 18 - 20 days later to repeat the two-day series of testing to be challenged with the exposure not received on the first series, (FA or O3). Each visit will take about 3 - 3.5 hours. Follow-up phone calls from the study team will occur at 24 hours after each 2-day test series. Total study duration is about one to one-and a half months.
Interventions
- DRUG Ozone
- OTHER Filtered Air
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2019-03-19 |
| Est. Completion | 2023-07-27 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03646877
The ClinicalTrials.gov registry entry for NCT03646877 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Robert Tighe, MD, which has 3 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Ozone is the first listed.
NCT03646877 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03646877 about?
NCT03646877 is a clinical study titled "Mechanisms of Ozone-Induced Alterations in Efferocytosis and Phagocytosis". The purpose of this research study to understand how environmental and genetic factors may be involved in lung function. Healthy Study participants will undergo a 1-day screening that includes a blood draw and breathing testing, return for a two-day series of testing to include blood draw, and brief...
What is the current status of trial NCT03646877?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 35 participants. The study started on 2019-03-19. Estimated completion is 2023-07-27.
What interventions are being tested in trial NCT03646877?
The interventions under investigation include: Ozone (DRUG), Filtered Air (OTHER).
Who is sponsoring clinical trial NCT03646877?
This trial is sponsored by Robert Tighe, MD, which has 3 total clinical trials registered on ClinicalTrials.gov.
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