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NCT03637049 · ClinicalTrials.gov registry record · Phase 1
Effect of PBI-4050 on the Pharmacokinetics of Midazolam in Heathy Adult Subjects
A Phase 1 study of Healthy, sponsored by Liminal BioSciences.
- Completed
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
- 1
- Study location
NCT03637049: Completed Phase 1 study of Healthy, sponsored by Liminal BioSciences.
NCT03637049 is a Phase 1 study of Healthy that has completed, run by Liminal BioSciences. The registered enrollment target is 22 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03637049, a Phase 1 study of Healthy, has completed, sponsored by Liminal BioSciences.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is designed to evaluate the pharmacokinetics (PK) and safety of multiple doses of PBI-4050 combined with midazolam in healthy adult subjects.
Primary Outcome
AUC0-t (AUC from time 0 to last observed non-zero concentration) of midazolam and 1-OH-midazolam assessed on Day 1 (Period 1) and Day 5 (Period 2)
Conditions Studied
Interventions
- DRUG PBI-4050 and midazolam
Study Locations (1)
Arizona
- Celerion - Tempe
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2018-07-17 |
| Est. Completion | 2018-08-22 |
| Phase | Phase 1 |
What the finished NCT03637049 record still lists
NCT03637049 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which PBI-4050 and midazolam is the first listed.
NCT03637049 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT03637049 about?
NCT03637049 is a clinical study titled "Effect of PBI-4050 on the Pharmacokinetics of Midazolam in Heathy Adult Subjects". This study is designed to evaluate the pharmacokinetics (PK) and safety of multiple doses of PBI-4050 combined with midazolam in healthy adult subjects.
What is the current status of trial NCT03637049?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2018-07-17. Estimated completion is 2018-08-22.
What conditions does trial NCT03637049 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT03637049?
The interventions under investigation include: PBI-4050 and midazolam (DRUG).
Who is sponsoring clinical trial NCT03637049?
This trial is sponsored by Liminal BioSciences, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03637049 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03637049's enrollment target sits among peer trials
22 844th of 1090 higher than 235 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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