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NCT03624478 · ClinicalTrials.gov registry record · Phase 2
Hypofractionated Radiation Therapy in Treating Participants With Breast Cancer Before Surgery
A Phase 2 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 2
- Development phase
- 25
- Enrollment target
NCT03624478: Completed Phase 2 study, sponsored by Mayo Clinic.
NCT03624478 is a Phase 2 study that has completed, run by Mayo Clinic. The registered enrollment target is 25 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03624478, a Phase 2 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 25 participants
- Enrollment target
Study Summary
This phase II trial studies how well hypofractionated radiation therapy works in treating participants with breast cancer before surgery. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects.
Primary Outcome
The proportion of successes (number of patients achieving pCR at time of definitive surgery) will be estimated by the number of successes divided by the total number of evaluable patients. Confidence intervals for the true success proportion will be calculated according to the approach of Duffy and Santner.
Interventions
- RADIATION Hypofractionated Radiation Therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2018-11-20 |
| Est. Completion | 2025-09-24 |
| Phase | Phase 2 |
What the finished NCT03624478 record still lists
NCT03624478 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower).
The record links to 0 conditions, and to 1 intervention - of which Hypofractionated Radiation Therapy is the first listed.
NCT03624478 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03624478 about?
NCT03624478 is a clinical study titled "Hypofractionated Radiation Therapy in Treating Participants With Breast Cancer Before Surgery". This phase II trial studies how well hypofractionated radiation therapy works in treating participants with breast cancer before surgery. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effe...
What is the current status of trial NCT03624478?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2018-11-20. Estimated completion is 2025-09-24.
What interventions are being tested in trial NCT03624478?
The interventions under investigation include: Hypofractionated Radiation Therapy (RADIATION).
Who is sponsoring clinical trial NCT03624478?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03624478's enrollment target sits among peer trials
25 1719th of 2000 higher than 245 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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