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NCT03610477 · ClinicalTrials.gov registry record · NA
MiCrobiome dieT Study
A NA study of Healthy, sponsored by University of Minnesota.
- Completed
- Registry status
- NA
- Development phase
- 34
- Enrollment target
- 1
- Study location
NCT03610477: Completed NA study of Healthy, sponsored by University of Minnesota.
NCT03610477 is a NA study of Healthy that has completed, run by University of Minnesota. The registered enrollment target is 34 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03610477, a NA study of Healthy, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- NA
- Development phase
- 34 participants
- Enrollment target
- 1
- Study location
Study Summary
The human gut microbiome is the community of bacteria that reside within the human intestine. These microbes are constantly exposed to the end-products and partial break-down-products of digestion from the foods consumed each day. Very little is known about the complex interaction of specific dietary components with the microbiome over time in one individual. In order to produce robust analysis of these interactions, longitudinal samples with detailed dietary intake information from healthy human subjects are needed. The complex relationship between dietary intake and the microbiome, and the potential health implications of human exposure to microbial metabolites, are only beginning to be understood. It is well known that altered dietary intake can trigger rapid, although transient, changes in the composition of the microbiome in as little as 1 to 2 days. The biggest factors in determining microbial response to diet are thought to include an individual's starting microbiome, long-term dietary habits, and environmental exposures. It is not well understood how small dietary differences from day-to-day impact the microbiome. A longitudinal dataset with accurately recorded dietary data and multiple samples over 17 days will provide valuable insight into the changes that occur at the individual level over time, while controlling for dietary trends and initial microbiome composition. Medium chain triglycerides (MCTs) have systemic beneficial effects and increase survival in rats by preventing gut injury and permeability following lipopolysaccharide administration, preventing alcohol-induced liver injury, and protecting against the development of colitis in a model of Crohn's disease. Understanding the interaction of MCTs with the microbiome in humans could lead to important advancements in the understanding of how diet impacts the microbiome composition, and ultimately, human health. This proposed study is designed to evaluate the effect of MCTs compared with long chai
Primary Outcome
Species-level compositional assessment
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Medium chain triglycerides
- DIETARY_SUPPLEMENT Long chain triglycerides
Study Locations (1)
Minnesota
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2017-01-01 |
| Est. Completion | 2017-12-30 |
| Phase | NA |
What the finished NCT03610477 record still lists
NCT03610477 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Medium chain triglycerides is the first listed.
NCT03610477 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT03610477 about?
NCT03610477 is a clinical study titled "MiCrobiome dieT Study". The human gut microbiome is the community of bacteria that reside within the human intestine. These microbes are constantly exposed to the end-products and partial break-down-products of digestion from the foods consumed each day. Very little is known about the complex interaction of specific dietar...
What is the current status of trial NCT03610477?
This trial is currently completed. It is a NA study. The enrollment target is 34 participants. The study started on 2017-01-01. Estimated completion is 2017-12-30.
What conditions does trial NCT03610477 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT03610477?
The interventions under investigation include: Medium chain triglycerides (DIETARY_SUPPLEMENT), Long chain triglycerides (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03610477?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03610477 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03610477's enrollment target sits among peer trials
34 631st of 1090 higher than 451 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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