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NCT03599206 · ClinicalTrials.gov registry record · Early Phase 1
ONES Grant: CXCL10/CXCR3 Regulation of Ozone-Induced Epithelial Permeability
A Early Phase 1 study of Environmental and Genetic Factors on Lung Function, sponsored by Robert Tighe, MD.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 14
- Enrollment target
- 1
- Study location
NCT03599206 is a Early Phase 1 study of Environmental and Genetic Factors on Lung Function that has completed, run by Robert Tighe, MD. The registered enrollment target is 14 participants. The trial reports 1 study location across 1 state.
The verdict
NCT03599206, a Early Phase 1 study of Environmental and Genetic Factors on Lung Function, has completed, sponsored by Robert Tighe, MD.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 14 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study to understand how environmental and genetic factors may be involved in lung function. Study participants will undergo a 1-day screening that includes a blood draw and breathing testing, return for a two-day series of testing to include blood draw, and brief breathing test before and after an inhaled challenge with either filtered air (FA) or ozone (O3). Participants return the next day for a brief breathing test, a blood draw and a procedure called bronchoscopy to evaluate the lung after the challenge. Participants then return 18 - 20 days later to repeat the two-day series of testing to be challenged with the exposure not received on the first series, (FA or O3). Each visit will take about 3 - 3.5 hours. Follow-up phone calls from the study team will occur at 24 hours after each 2-day test series. Total study duration is about one to one-and a half months.
Conditions Studied
Interventions
- DRUG Ozone
- OTHER Filtered Air
Study Locations (1)
North Carolina
- Duke Asthma, Allergy, and Airway Center - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2019-08-16 |
| Est. Completion | 2024-01-24 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03599206
The ClinicalTrials.gov registry entry for NCT03599206 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Robert Tighe, MD, which has 3 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Environmental and Genetic Factors on Lung Function appearing as the primary indexed condition, and to 2 interventions - of which Ozone is the first listed.
NCT03599206 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT03599206 about?
NCT03599206 is a clinical study titled "ONES Grant: CXCL10/CXCR3 Regulation of Ozone-Induced Epithelial Permeability". The purpose of this research study to understand how environmental and genetic factors may be involved in lung function. Study participants will undergo a 1-day screening that includes a blood draw and breathing testing, return for a two-day series of testing to include blood draw, and brief breathi...
What is the current status of trial NCT03599206?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 14 participants. The study started on 2019-08-16. Estimated completion is 2024-01-24.
What conditions does trial NCT03599206 study?
This clinical trial studies the following conditions: Environmental and Genetic Factors on Lung Function.
What interventions are being tested in trial NCT03599206?
The interventions under investigation include: Ozone (DRUG), Filtered Air (OTHER).
Who is sponsoring clinical trial NCT03599206?
This trial is sponsored by Robert Tighe, MD, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03599206 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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