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NCT03576508 · ClinicalTrials.gov registry record · Phase 1
A Study to Compare Levels of Capsaicin After Intra-Articular Injection and Topical Application in Patients With Painful Knee Osteoarthritis
A Phase 1 study of Knee Osteoarthritis, sponsored by Centrexion Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT03576508: Completed Phase 1 study of Knee Osteoarthritis, sponsored by Centrexion Therapeutics.
NCT03576508 is a Phase 1 study of Knee Osteoarthritis that has completed, run by Centrexion Therapeutics. The registered enrollment target is 16 participants, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03576508, a Phase 1 study of Knee Osteoarthritis, has completed, sponsored by Centrexion Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a Phase 1b, open-label, two-period, randomized crossover study in adult male and female participants with painful knee osteoarthritis.
Primary Outcome
Single-dose systemic exposure to trans- and cis-capsaicin measured by AUC0-t.
Conditions Studied
Interventions
- DRUG CNTX-4975-05
- DRUG Qutenza
- DRUG Lidocaine (without epinephrine)
Study Locations (1)
Florida
- Well Pharma Medical Research, Corp - Miami
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2018-06-25 |
| Est. Completion | 2018-09-06 |
| Phase | Phase 1 |
What the finished NCT03576508 record still lists
NCT03576508 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Knee Osteoarthritis appearing as the primary indexed condition, and to 3 interventions - of which CNTX-4975-05 is the first listed.
NCT03576508 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT03576508 about?
NCT03576508 is a clinical study titled "A Study to Compare Levels of Capsaicin After Intra-Articular Injection and Topical Application in Patients With Painful Knee Osteoarthritis". This is a Phase 1b, open-label, two-period, randomized crossover study in adult male and female participants with painful knee osteoarthritis.
What is the current status of trial NCT03576508?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2018-06-25. Estimated completion is 2018-09-06.
What conditions does trial NCT03576508 study?
This clinical trial studies the following conditions: Knee Osteoarthritis.
What interventions are being tested in trial NCT03576508?
The interventions under investigation include: CNTX-4975-05 (DRUG), Qutenza (DRUG), Lidocaine (without epinephrine) (DRUG).
Who is sponsoring clinical trial NCT03576508?
This trial is sponsored by Centrexion Therapeutics, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03576508 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03576508's enrollment target sits among peer trials
16 95th of 101 higher than 5 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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