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NCT05906433 · ClinicalTrials.gov registry record · Phase 1
Optimal Anesthetic for Corticosteroid Injections for Knee Osteoarthritis
A Phase 1 study of Knee Osteoarthritis, sponsored by Foundation for Orthopaedic Research and Education.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT05906433: Recruiting Phase 1 study of Knee Osteoarthritis, sponsored by Foundation for Orthopaedic Research and Education.
NCT05906433 is a Phase 1 study of Knee Osteoarthritis that is actively recruiting participants, run by Foundation for Orthopaedic Research and Education. The registered enrollment target is 75 participants, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05906433, a Phase 1 study of Knee Osteoarthritis, is actively recruiting participants, sponsored by Foundation for Orthopaedic Research and Education.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
To evaluate pain relief from corticosteroid injection with and without anesthetic as well as with variable volume of anesthetic. Pain relief will be measured using the VAS pain score at the time of the injection as well as several time points following the injection to capture pain relief longevity. The investigators intend to evaluate how well the patients tolerate corticosteroid mixtures without anesthetic as well as with different volumes of anesthetic. Primary measure will be the time from procedure when postoperative status is considered success (as measured by global perceived improvement score).
Primary Outcome
Visual Analogue Scale (VAS)
Conditions Studied
Interventions
- DRUG Kenalog with bupivacaine Injection
Study Locations (1)
Florida
- Florida Orthopaedic Institute - Tampa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2023-06-01 |
| Est. Completion | 2025-12-01 |
| Phase | Phase 1 |
What NCT05906433 shows while recruiting
NCT05906433 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (75% lower).
The record links to 1 condition, with Knee Osteoarthritis appearing as the primary indexed condition, and to 1 intervention - of which Kenalog with bupivacaine Injection is the first listed.
NCT05906433 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT05906433 about?
NCT05906433 is a clinical study titled "Optimal Anesthetic for Corticosteroid Injections for Knee Osteoarthritis". To evaluate pain relief from corticosteroid injection with and without anesthetic as well as with variable volume of anesthetic. Pain relief will be measured using the VAS pain score at the time of the injection as well as several time points following the injection to capture pain relief longevity....
What is the current status of trial NCT05906433?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 75 participants. The study started on 2023-06-01. Estimated completion is 2025-12-01.
What conditions does trial NCT05906433 study?
This clinical trial studies the following conditions: Knee Osteoarthritis.
What interventions are being tested in trial NCT05906433?
The interventions under investigation include: Kenalog with bupivacaine Injection (DRUG).
Who is sponsoring clinical trial NCT05906433?
This trial is sponsored by Foundation for Orthopaedic Research and Education, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05906433 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05906433's enrollment target sits among peer trials
75 52nd of 101 higher than 49 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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