Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03543098 · ClinicalTrials.gov registry record · NA
STaR Trial: Multiple Ligament Knee Injuries
A NA study of Knee Dislocations and Multiple Ligament Knee Injuries, sponsored by University of Pittsburgh.
- Active
- Registry status
- NA
- Development phase
- 690
- Enrollment target
- 1
- Study location
NCT03543098: Active NA study of Knee Dislocations and Multiple Ligament Knee Injuries, sponsored by University of Pittsburgh.
NCT03543098 is a NA study of Knee Dislocations and Multiple Ligament Knee Injuries that is active but no longer recruiting, run by University of Pittsburgh. The registered enrollment target is 690 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03543098, a NA study of Knee Dislocations and Multiple Ligament Knee Injuries, is active but no longer recruiting, sponsored by University of Pittsburgh.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 690 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate effects of timing of surgery (early vs. delayed) and timing of post-operative rehabilitation (early vs. delayed) for the treatment of military personnel and civilians that sustain a multiple ligament knee injury. To achieve this overall objective of this project, we will conduct two parallel randomized clinical trials. For the first study we will randomize individuals to timing of surgery and timing of post-operative rehabilitation. We hypothesize that early surgery, early rehabilitation and the combination of early surgery with early rehabilitation will lead to an earlier and more complete return to pre-injury military duty, work and sports and better patient-reported physical function. In the second study, those whose timing of surgery can not be randomized, will be only randomized to early or delayed rehabilitation. For this study, we hypothesize that early rehabilitation will lead to an earlier and more complete return to pre-injury military duty, work and sports activity and better patient-reported physical function.
Primary Outcome
Time to return to pre-injury level military duty, work and/ sports
Conditions Studied
Interventions
- PROCEDURE Early Surgery
- PROCEDURE Delayed Surgery
- PROCEDURE Early Rehab
- PROCEDURE Delayed Rehab
Study Locations (1)
Pennsylvania
- University of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 690 participants |
| Start Date | 2018-07-31 |
| Est. Completion | 2027-06 |
| Phase | NA |
What the registry record for NCT03543098 still lists
NCT03543098 is an interventional study that assigns participants to a tested intervention. The registered 690 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (51% lower).
The record links to 2 conditions, with Knee Dislocations appearing as the primary indexed condition, and to 4 interventions - of which Early Surgery is the first listed.
NCT03543098 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03543098 about?
NCT03543098 is a clinical study titled "STaR Trial: Multiple Ligament Knee Injuries". The purpose of this study is to investigate effects of timing of surgery (early vs. delayed) and timing of post-operative rehabilitation (early vs. delayed) for the treatment of military personnel and civilians that sustain a multiple ligament knee injury. To achieve this overall objective of this p...
What is the current status of trial NCT03543098?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 690 participants. The study started on 2018-07-31. Estimated completion is 2027-06.
What conditions does trial NCT03543098 study?
This clinical trial studies the following conditions: Knee Dislocations, Multiple Ligament Knee Injuries.
What interventions are being tested in trial NCT03543098?
The interventions under investigation include: Early Surgery (PROCEDURE), Delayed Surgery (PROCEDURE), Early Rehab (PROCEDURE), Delayed Rehab (PROCEDURE).
Who is sponsoring clinical trial NCT03543098?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03543098 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03543098's enrollment target sits among peer trials
690 151st of 2000 higher than 1,850 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00532051 · 690 participants
Intraocular Lens Power Calculation After Laser Refractive Surgery Based on Optical Coherence Tomography
- NCT05184335 · 690 participants · Phase 3
Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia
- NCT07221149 · 690 participants · Phase 2
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)
- NCT07382167 · 692 participants · Phase 3
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI