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NCT03539770 · ClinicalTrials.gov registry record
Lung Regeneration After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis
A clinical trial, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- 29
- Enrollment target
NCT03539770: Completed study, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT03539770 is a clinical trial that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 29 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03539770 has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- 29 participants
- Enrollment target
Study Summary
Adolescent Idiopathic Scoliosis (AIS) is a curvature of the spine that occurs in 1-2% of otherwise healthy children, and requires corrective surgery, posterior spinal fusion (PSF) in \~10% of cases. Some studies suggest that pulmonary function is reduced in AIS and that PSF improves pulmonary function. The lung is composed of a large number of branching airways that terminate in gas exchanging units called alveoli, and the number and structure of these alveoli are partially dependent upon lung volume and the forces to which they are exposed--two factors predicted to be altered in AIS. This study uses MRI imaging of inhaled helium to quantify alveolar structure in children with and without AIS before and one-year after PSF. The goals of the study are to determine if alveolar architecture or number are altered in AIS and whether PSF impacts these same measures.
Primary Outcome
Calculated mean linear intercept as determined by diffusion measurements in HHe MRI
Interventions
- PROCEDURE Posterior spinal fusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2014-11-01 |
| Est. Completion | 2018-05-31 |
What the finished NCT03539770 record still lists
NCT03539770 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 29 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Posterior spinal fusion is the first listed.
NCT03539770 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03539770 about?
NCT03539770 is a clinical study titled "Lung Regeneration After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis". Adolescent Idiopathic Scoliosis (AIS) is a curvature of the spine that occurs in 1-2% of otherwise healthy children, and requires corrective surgery, posterior spinal fusion (PSF) in \~10% of cases. Some studies suggest that pulmonary function is reduced in AIS and that PSF improves pulmonary functi...
What is the current status of trial NCT03539770?
This trial is currently completed. The enrollment target is 29 participants. The study started on 2014-11-01. Estimated completion is 2018-05-31.
What interventions are being tested in trial NCT03539770?
The interventions under investigation include: Posterior spinal fusion (PROCEDURE).
Who is sponsoring clinical trial NCT03539770?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
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