Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03537703 · ClinicalTrials.gov registry record · NA

Transcranial Direct Current Stimulation and Effects on Early Auditory Processing in Schizophrenia

A NA study, sponsored by VA Greater Los Angeles Healthcare System.

Completed
Registry status
NA
Development phase
35
Enrollment target

NCT03537703: Completed NA study, sponsored by VA Greater Los Angeles Healthcare System.

NCT03537703 is a NA study that has completed, run by VA Greater Los Angeles Healthcare System. The registered enrollment target is 35 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03537703, a NA study, has completed, sponsored by VA Greater Los Angeles Healthcare System.

COMPLETED
Registry status
NA
Development phase
35 participants
Enrollment target

Study Summary

Individuals with schizophrenia have difficulties in functioning in the community. No one really knows what factors determine how well patients manage in the real world. The purpose of this pilot study is to try a new approach to improving a potential determinant of good community functioning, namely how we process sounds. Specifically, the investigators propose to examine the benefit of combining auditory training exercises with transcranial direct current stimulation (tDCS). tDCS is a new tool that is being developed as a safe and noninvasive neurostimulation method, for improving processing of sounds. Transcranial direct current stimulation involves placing a wet sponge electrode on the head and one on the arm. Electrical current from a device powered by a 9-volt battery will flow from one electrode to the other. A small portion of the current will pass through the skull and stimulate the brain. This procedure is non-invasive and painless and it results in increase or decrease of spontaneous neuronal firing in the brain. Neurons are brain cells that send electrochemical messages to each other. Its safety and beneficial effect on mental functions has been demonstrated in healthy individuals and several clinical populations. The purpose of this study is to determine if transcranial direct current stimulation added to auditory training exercises can improve how schizophrenia patients process sound.

Primary Outcome

Performance based measure of tone discrimination

Interventions

  • COMBINATION_PRODUCT Active tDCS + Auditory Training
  • COMBINATION_PRODUCT Active tDCS + Control Condition
  • COMBINATION_PRODUCT Sham tDCS + Auditory Training

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2018-05-20
Est. Completion 2020-05-01
Phase NA

What the finished NCT03537703 record still lists

NCT03537703 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 3 interventions - of which Active tDCS + Auditory Training is the first listed.

NCT03537703 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03537703 about?

NCT03537703 is a clinical study titled "Transcranial Direct Current Stimulation and Effects on Early Auditory Processing in Schizophrenia". Individuals with schizophrenia have difficulties in functioning in the community. No one really knows what factors determine how well patients manage in the real world. The purpose of this pilot study is to try a new approach to improving a potential determinant of good community functioning, namely...

What is the current status of trial NCT03537703?

This trial is currently completed. It is a NA study. The enrollment target is 35 participants. The study started on 2018-05-20. Estimated completion is 2020-05-01.

What interventions are being tested in trial NCT03537703?

The interventions under investigation include: Active tDCS + Auditory Training (COMBINATION_PRODUCT), Active tDCS + Control Condition (COMBINATION_PRODUCT), Sham tDCS + Auditory Training (COMBINATION_PRODUCT).

Who is sponsoring clinical trial NCT03537703?

This trial is sponsored by VA Greater Los Angeles Healthcare System, which has 23 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03537703's enrollment target sits among peer trials

35 1564th of 2000 higher than 431 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01697371 · 35 participants · NA

    Proton Therapy in the Treatment of Liver Metastases

  • NCT01940757 · 35 participants · Phase 1

    Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae

  • NCT02235857 · 35 participants · NA

    Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

  • NCT02637934 · 35 participants · Phase 1

    Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03537703, the US trial registry maintained by the National Library of Medicine. NCT03537703 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.