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NCT03513497 · ClinicalTrials.gov registry record · NA
IFI16 is a Periodontitis Modulating Protein
A NA study of Severe Periodontitis and Acute Inflammatory Response, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 69
- Enrollment target
- 1
- Study location
NCT03513497 is a NA study of Severe Periodontitis and Acute Inflammatory Response that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 69 participants. The trial reports 1 study location across 1 state.
The verdict
NCT03513497, a NA study of Severe Periodontitis and Acute Inflammatory Response, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 69 participants
- Enrollment target
- 1
- Study location
Study Summary
To characterize the expression of Interferon gamma inducible protein 16 (IFI16) and Absent in melanoma 2 (AIM2) in gingival tissues in an inflammatory response using an acrylic mouthguard (also referred to as a stent) induced bacteria overgrowth method. Participants: A maximum of 72 Adult subjects will be recruited from the patients, students and staff at the University of North Carolina, as well as the general population in or near Chapel Hill NC. Procedures (methods): Medical history, demographics, (height/weight), urine based pregnancy test, vital signs (to include blood pressures, and pulse) standard dental clinical measures (to include plaque index, gingival index, bleeding on probing, and clinical attachment level), alginate impressions taken for fabrication of an acrylic stent (mouthguard), 2 gingival biopsies, 2 subgingival (below the gumline) plaque samples, and Scaling Root planing (SRP)/or adult prophylaxis
Conditions Studied
Interventions
- OTHER Customized acrylic mouthguard
Study Locations (1)
North Carolina
- University of North Carolina at Chapel Hill - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 69 participants |
| Start Date | 2018-10-18 |
| Est. Completion | 2023-06-28 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03513497
The ClinicalTrials.gov registry entry for NCT03513497 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 69 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Severe Periodontitis appearing as the primary indexed condition, and to 1 intervention - of which Customized acrylic mouthguard is the first listed.
NCT03513497 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT03513497 about?
NCT03513497 is a clinical study titled "IFI16 is a Periodontitis Modulating Protein". To characterize the expression of Interferon gamma inducible protein 16 (IFI16) and Absent in melanoma 2 (AIM2) in gingival tissues in an inflammatory response using an acrylic mouthguard (also referred to as a stent) induced bacteria overgrowth method. Participants: A maximum of 72 Adult subjects ...
What is the current status of trial NCT03513497?
This trial is currently completed. It is a NA study. The enrollment target is 69 participants. The study started on 2018-10-18. Estimated completion is 2023-06-28.
What conditions does trial NCT03513497 study?
This clinical trial studies the following conditions: Severe Periodontitis, Acute Inflammatory Response.
What interventions are being tested in trial NCT03513497?
The interventions under investigation include: Customized acrylic mouthguard (OTHER).
Who is sponsoring clinical trial NCT03513497?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03513497 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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