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NCT03489590 · ClinicalTrials.gov registry record · Early Phase 1

19F MRI to Evaluate Regional Ventilation in Healthy Subjects and Subjects With Cystic Fibrosis

A Early Phase 1 study of Cystic Fibrosis, sponsored by University of North Carolina, Chapel Hill.

Completed
Registry status
Early Phase 1
Development phase
42
Enrollment target
1
Study location

NCT03489590 is a Early Phase 1 study of Cystic Fibrosis that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 42 participants, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03489590, a Early Phase 1 study of Cystic Fibrosis, has completed, sponsored by University of North Carolina, Chapel Hill.

COMPLETED
Registry status
Early Phase 1
Development phase
42 participants
Enrollment target
1
Study location

Study Summary

An open label non-randomized study enrolling up to 20 healthy participants and up to 30 participants with cystic fibrosis to establish a healthy versus disease comparison. Each participant will receive a mixture of inert gas (perfluoropropane (PFP)) in a ratio of 79% PFP to 21% oxygen as a contrast agent to enhance visualization of the airway and alveolar spaces using magnetic resonance imaging of inert gas/oxygen mixtures. The study consists of a screening visit followed by up to 2 study visits.

Conditions Studied

Interventions

  • DRUG PFP

Study Locations (1)

North Carolina

  • The University of North Carolina at Chapel Hill - Chapel Hill

Trial Details

FieldValue
Enrollment Target 42 participants
Start Date 2015-07-01
Est. Completion 2018-12-31
Phase Early Phase 1

What the Registry Record Tells You About NCT03489590

The ClinicalTrials.gov registry entry for NCT03489590 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (77% lower). The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cystic Fibrosis appearing as the primary indexed condition, and to 1 intervention - of which PFP is the first listed.

NCT03489590 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT03489590 about?

NCT03489590 is a clinical study titled "19F MRI to Evaluate Regional Ventilation in Healthy Subjects and Subjects With Cystic Fibrosis". An open label non-randomized study enrolling up to 20 healthy participants and up to 30 participants with cystic fibrosis to establish a healthy versus disease comparison. Each participant will receive a mixture of inert gas (perfluoropropane (PFP)) in a ratio of 79% PFP to 21% oxygen as a contrast ...

What is the current status of trial NCT03489590?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 42 participants. The study started on 2015-07-01. Estimated completion is 2018-12-31.

What conditions does trial NCT03489590 study?

This clinical trial studies the following conditions: Cystic Fibrosis.

What interventions are being tested in trial NCT03489590?

The interventions under investigation include: PFP (DRUG).

Who is sponsoring clinical trial NCT03489590?

This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03489590 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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