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NCT06527222 · ClinicalTrials.gov registry record · Phase 2

A Study of Ranolazine in ALS

A Phase 2 study of Amyotrophic Lateral Sclerosis, sponsored by Swathy Chandrashekhar, MBBS.

Recruiting
Registry status
Phase 2
Development phase
72
Enrollment target
7
Study locations

NCT06527222 is a Phase 2 study of Amyotrophic Lateral Sclerosis that is actively recruiting participants, run by Swathy Chandrashekhar, MBBS. The registered enrollment target is 72 participants, below the 897-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (92% lower). The trial reports 7 study locations across 6 states.

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The verdict

NCT06527222, a Phase 2 study of Amyotrophic Lateral Sclerosis, is actively recruiting participants, sponsored by Swathy Chandrashekhar, MBBS.

RECRUITING
Registry status
Phase 2
Development phase
72 participants
Enrollment target
7
Study locations

Study Summary

The purpose of this study is to evaluate safety, effect on cramps, function and quality of life of ranolazine versus placebo for the treatment of ALS.

Conditions Studied

Amyotrophic Lateral Sclerosis

Interventions

  • DRUG Placebo
  • DRUG Ranolazine

Study Locations (7)

Kansas

  • University of Kansas Medical Center - Fairway
  • University of Kansas Medical Center: Wichita - Wichita

California

  • University of California, San Francisco - San Francisco

Florida

  • Mayo Clinic Florida - Jacksonville

Missouri

  • University of Missouri Health Care - Columbia

Ohio

  • The Ohio State University - Columbus

Texas

  • National Neuromuscular Research Institute, PLLC. - Austin

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2025-04-29
Est. Completion 2026-05
Phase Phase 2

Sponsor

Swathy Chandrashekhar, MBBS

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06527222

The ClinicalTrials.gov registry entry for NCT06527222 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 897-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (92% lower). The listed sponsor is Swathy Chandrashekhar, MBBS, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Amyotrophic Lateral Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06527222 reports 7 study locations spanning 6 distinct geographic areas - top geographies include Kansas, California, Florida.

Frequently Asked Questions

What is clinical trial NCT06527222 about?

NCT06527222 is a clinical study titled "A Study of Ranolazine in ALS". The purpose of this study is to evaluate safety, effect on cramps, function and quality of life of ranolazine versus placebo for the treatment of ALS.

What is the current status of trial NCT06527222?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 72 participants. The study started on 2025-04-29. Estimated completion is 2026-05.

What conditions does trial NCT06527222 study?

This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis.

What interventions are being tested in trial NCT06527222?

The interventions under investigation include: Placebo (DRUG), Ranolazine (DRUG).

Who is sponsoring clinical trial NCT06527222?

This trial is sponsored by Swathy Chandrashekhar, MBBS, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06527222 being conducted?

This trial has 7 study locations across California, Florida, Kansas, Missouri, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.