Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03455959 · ClinicalTrials.gov registry record · NA
Lung-Resident Memory Th2 Cells in Asthma
A NA study of Asthma, Allergic, sponsored by Andrew D. Luster, M.D.,Ph.D..
- Active
- Registry status
- NA
- Development phase
- 37
- Enrollment target
- 1
- Study location
NCT03455959 is a NA study of Asthma, Allergic that is active but no longer recruiting, run by Andrew D. Luster, M.D.,Ph.D.. The registered enrollment target is 37 participants. The trial reports 1 study location across 1 state.
The verdict
NCT03455959, a NA study of Asthma, Allergic, is active but no longer recruiting, sponsored by Andrew D. Luster, M.D.,Ph.D..
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 37 participants
- Enrollment target
- 1
- Study location
Study Summary
Determining how memory T helper type 2 (Th2) initiate recall responses to aeroallergens has the potential to change the therapeutic approach to allergic asthma, the most common asthma subtype. \~5-10% of effector Th2 cells recruited into the lung give rise to long-lived tissue resident memory cells that are poised to respond upon allergen re-exposure.Consequently, targeting memory Th2 cell activation is an attractive therapeutic strategy. However, it is not well understood how allergen inhalation initiates a memory Th2 cell response in the lung. The focus of this new study on the role of lung-resident memory Th2 cells in orchestrating the recall response to allergen in the lung, including the recruitment and activation of circulating Th2 cells, is a natural, timely and exciting extension of the investigators' ongoing Allergen Challenge Protocol.
Conditions Studied
Interventions
- PROCEDURE Bronchoscopy/BAL
- PROCEDURE Airway Brushing
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2019-05-23 |
| Est. Completion | 2025-12-15 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03455959
The ClinicalTrials.gov registry entry for NCT03455959 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Andrew D. Luster, M.D.,Ph.D., which has 3 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Asthma, Allergic appearing as the primary indexed condition, and to 2 interventions - of which Bronchoscopy/BAL is the first listed.
NCT03455959 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT03455959 about?
NCT03455959 is a clinical study titled "Lung-Resident Memory Th2 Cells in Asthma". Determining how memory T helper type 2 (Th2) initiate recall responses to aeroallergens has the potential to change the therapeutic approach to allergic asthma, the most common asthma subtype. \~5-10% of effector Th2 cells recruited into the lung give rise to long-lived tissue resident memory cells ...
What is the current status of trial NCT03455959?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 37 participants. The study started on 2019-05-23. Estimated completion is 2025-12-15.
What conditions does trial NCT03455959 study?
This clinical trial studies the following conditions: Asthma, Allergic.
What interventions are being tested in trial NCT03455959?
The interventions under investigation include: Bronchoscopy/BAL (PROCEDURE), Airway Brushing (PROCEDURE).
Who is sponsoring clinical trial NCT03455959?
This trial is sponsored by Andrew D. Luster, M.D.,Ph.D., which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03455959 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Asthma, Allergic
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.