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NCT03449979 · ClinicalTrials.gov registry record · NA
Single Session of tACS in a Depressive Episode
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 84
- Enrollment target
NCT03449979: Completed NA study, sponsored by University of North Carolina, Chapel Hill.
NCT03449979 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 84 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03449979, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 84 participants
- Enrollment target
Study Summary
Purpose: Investigating the effects of non-invasive transcranial alternating current stimulation (tACS) on healthy participants and participants with mood disorders. Participants: 40 males and females, ages 18-65, with depressed mood; 40 healthy males and females, ages 18-65, free of neurological or psychiatric conditions. Procedures: This is a single visit study with two stimulation conditions (tACS and sham tACS). The session will begin with clinical assessments (including confirmation of diagnosis), followed by an interactive EEG task, then a 7 minute resting state EEG (2 minutes eyes closed, 5 minutes eyes open), followed by the stimulation session (40 minutes of tACS or sham tACS), followed by an additional 5 minute resting state EEG. The stimulation will involved 40 minutes of transcranial alternating current stimulation, 2 mA in amplitude and at individualized alpha frequency (determined by the 2 minutes eyes closed EEG recording; between 8 and 12Hz).
Primary Outcome
Fast Fourier transform is applied to 5 minutes of EEG data before and after intervention. Primary outcome is the difference in alpha frequency amplitude (8-12 Hz) in the left frontal cortex from baseline as a result of intervention.
Interventions
- DEVICE XCSITE100 Stimulator tACS
- DEVICE XCSITE100 Stimulator Sham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2018-09-19 |
| Est. Completion | 2019-08-16 |
| Phase | NA |
What the finished NCT03449979 record still lists
NCT03449979 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 2 interventions - of which XCSITE100 Stimulator tACS is the first listed.
NCT03449979 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03449979 about?
NCT03449979 is a clinical study titled "Single Session of tACS in a Depressive Episode". Purpose: Investigating the effects of non-invasive transcranial alternating current stimulation (tACS) on healthy participants and participants with mood disorders. Participants: 40 males and females, ages 18-65, with depressed mood; 40 healthy males and females, ages 18-65, free of neurological or...
What is the current status of trial NCT03449979?
This trial is currently completed. It is a NA study. The enrollment target is 84 participants. The study started on 2018-09-19. Estimated completion is 2019-08-16.
What interventions are being tested in trial NCT03449979?
The interventions under investigation include: XCSITE100 Stimulator tACS (DEVICE), XCSITE100 Stimulator Sham (DEVICE).
Who is sponsoring clinical trial NCT03449979?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03449979's enrollment target sits among peer trials
84 983rd of 2000 higher than 1,011 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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