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NCT03438461 · ClinicalTrials.gov registry record · Phase 1

A Study to Evaluate the Relative Oral Bioavailability of Seltorexant (JNJ-42847922) After Administration of 3 Different Formulations in Healthy Participants Under Fasted and Semi-fasted Conditions

A Phase 1 study of Healthy, sponsored by Janssen Research & Development.

Completed
Registry status
Phase 1
Development phase
49
Enrollment target
1
Study location

NCT03438461 is a Phase 1 study of Healthy that has completed, run by Janssen Research & Development. The registered enrollment target is 49 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03438461, a Phase 1 study of Healthy, has completed, sponsored by Janssen Research & Development.

COMPLETED
Registry status
Phase 1
Development phase
49 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to assess and compare the pharmacokinetics (PK) and relative oral bioavailability of 3 oral tablet formulations of seltorexant in fasted and semi-fasted conditions.

Conditions Studied

Interventions

  • DRUG Seltorexant 40 mg
  • DRUG Seltorexant 20 mg

Study Locations (1)

Utah

  • PRAHS - Salt Lake City

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2018-02-09
Est. Completion 2018-05-30
Phase Phase 1

Sponsor

Janssen Research & Development

593 total trials

What the Registry Record Tells You About NCT03438461

The ClinicalTrials.gov registry entry for NCT03438461 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 49 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (92% lower). The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Seltorexant 40 mg is the first listed.

NCT03438461 reports 1 study location spanning 1 distinct geographic area - top geographies include Utah.

Frequently Asked Questions

What is clinical trial NCT03438461 about?

NCT03438461 is a clinical study titled "A Study to Evaluate the Relative Oral Bioavailability of Seltorexant (JNJ-42847922) After Administration of 3 Different Formulations in Healthy Participants Under Fasted and Semi-fasted Conditions". The purpose of this study is to assess and compare the pharmacokinetics (PK) and relative oral bioavailability of 3 oral tablet formulations of seltorexant in fasted and semi-fasted conditions.

What is the current status of trial NCT03438461?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 49 participants. The study started on 2018-02-09. Estimated completion is 2018-05-30.

What conditions does trial NCT03438461 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT03438461?

The interventions under investigation include: Seltorexant 40 mg (DRUG), Seltorexant 20 mg (DRUG).

Who is sponsoring clinical trial NCT03438461?

This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03438461 being conducted?

This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.