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NCT03437486 · ClinicalTrials.gov registry record
Mechanisms of Familial Pulmonary Fibrosis
A clinical trial of Idiopathic Pulmonary Fibrosis and Familial Pulmonary Fibrosis, sponsored by Vanderbilt University Medical Center.
- Recruiting
- Registry status
- 750
- Enrollment target
- 1
- Study location
NCT03437486 is a study of Idiopathic Pulmonary Fibrosis and Familial Pulmonary Fibrosis that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 750 participants, roughly in line with the 737-participant average among 51 other Idiopathic Pulmonary Fibrosis trials with a reported enrollment target. The trial reports 1 study location across 1 state.
The verdict
NCT03437486, a study of Idiopathic Pulmonary Fibrosis and Familial Pulmonary Fibrosis, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.
- RECRUITING
- Registry status
- 750 participants
- Enrollment target
- 1
- Study location
Study Summary
This a prospective, longitudinal study of first-degree family members of patients diagnosed with familial interstitial pneumonia (FIP). FIP is the familial form of idiopathic pulmonary fibrosis (IPF), which is defined as 2 or more bloodline relatives which have a diagnosis of idiopathic interstitial pneumonia (IIP). The most common form of idiopathic interstitial pneumonia in FIP families is IPF (approximately 70%). The inheritance pattern in FIP is consistent with autosomal dominant inheritance with incomplete penetrance. Therefore, individuals in this study have approximately 50% risk of carrying a disease-associated allele. The causative gene is currently only known approximately 20% of families. The main goal of this longitudinal study is to better establish the natural history of FIP and to identify risk factors for later development of symptomatic disease. The investigators' plan is to follow these at-risk individuals with yearly questionnaires and planned in person 2 year follow-ups through age 75 or until they develop symptomatic FIP.
Conditions Studied
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 750 participants |
| Start Date | 2009-01-01 |
| Est. Completion | 2030-01-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03437486
The ClinicalTrials.gov registry entry for NCT03437486 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 750 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 737-participant average among 51 other Idiopathic Pulmonary Fibrosis trials with a reported enrollment target. The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Idiopathic Pulmonary Fibrosis appearing as the primary indexed condition, and to 0 interventions.
NCT03437486 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT03437486 about?
NCT03437486 is a clinical study titled "Mechanisms of Familial Pulmonary Fibrosis". This a prospective, longitudinal study of first-degree family members of patients diagnosed with familial interstitial pneumonia (FIP). FIP is the familial form of idiopathic pulmonary fibrosis (IPF), which is defined as 2 or more bloodline relatives which have a diagnosis of idiopathic interstitial...
What is the current status of trial NCT03437486?
This trial is currently recruiting. The enrollment target is 750 participants. The study started on 2009-01-01. Estimated completion is 2030-01-30.
What conditions does trial NCT03437486 study?
This clinical trial studies the following conditions: Idiopathic Pulmonary Fibrosis, Familial Pulmonary Fibrosis, Familial Interstitial Pneumonia.
Who is sponsoring clinical trial NCT03437486?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03437486 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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