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RECRUITING Phase 2

A Phase 2 Study of CAL101 in Patients With Idiopathic Pulmonary Fibrosis

NCT06736990 · View on ClinicalTrials.gov ↗

Study Summary

The goal of this clinical trial is to learn if the investigational drug CAL101 can help prevent further decline in lung function in adults with Idiopathic Pulmonary Fibrosis. Researchers will compare CAL101 with placebo to compare change from baseline in forced vital capacity (FVC). Participants will be randomly assigned to a study group that will receive an IV infusion of either the study medication or placebo about once a month for 6 months.

Interventions

  • DRUG Placebo
  • DRUG CAL101

Study Locations (20)

Other

  • Aarhus University Hospital — Aarhus
  • Rigshospitalet — Copenhagen
  • Odense University Hospital — Odense
  • AP-HP Hopital Avicenne — Bobigny
  • AP-HP Hopital Europeen Georges Pompidou — Paris
  • CHU Rennes - Hopital Pontchaillou — Rennes
  • CHU de Toulouse - Hopital Larrey — Toulouse
  • CHRU de Tours - Hôpital Bretonneau — Tours

North Carolina

  • Pulmonix, LLC — Greensboro
  • Southeastern Research Center — Winston-Salem

California

  • Keck School of Medicine at USC — Los Angeles

Colorado

  • National Jewish Health — Denver

Florida

  • Y & L Advance Health Care, Inc. d/b/a Elite Clinical Research — Miami

Kansas

  • University of Kansas Medical Center — Kansas City

Ohio

  • Cleveland Clinic — Cleveland

Pennsylvania

  • Temple University Hospital — Philadelphia

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2025-06-20
Est. Completion 2027-11
Phase Phase 2

Sponsor

Calluna Pharma AS

29 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06736990

The ClinicalTrials.gov registry entry for NCT06736990 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Calluna Pharma AS, which has 29 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Idiopathic Pulmonary Fibrosis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06736990 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Other, North Carolina, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06736990 about?

NCT06736990 is a clinical study titled "A Phase 2 Study of CAL101 in Patients With Idiopathic Pulmonary Fibrosis". The goal of this clinical trial is to learn if the investigational drug CAL101 can help prevent further decline in lung function in adults with Idiopathic Pulmonary Fibrosis. Researchers will compare CAL101 with placebo to compare change from baseline in forced vital capacity (FVC). Participants w...

What is the current status of trial NCT06736990?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 150 participants. The study started on 2025-06-20. Estimated completion is 2027-11.

What conditions does trial NCT06736990 study?

This clinical trial studies the following conditions: Idiopathic Pulmonary Fibrosis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06736990?

The interventions under investigation include: Placebo (DRUG), CAL101 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06736990?

This trial is sponsored by Calluna Pharma AS, which has 29 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06736990 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Kansas, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial