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NCT03437005 · ClinicalTrials.gov registry record · Phase 1

Alternation in the Human Microbiome With Commonly Used Topical Medications

A Phase 1 study of Healthy, sponsored by University of California, Davis.

Recruiting
Registry status
Phase 1
Development phase
24
Enrollment target
1
Study location

NCT03437005 is a Phase 1 study of Healthy that is actively recruiting participants, run by University of California, Davis. The registered enrollment target is 24 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03437005, a Phase 1 study of Healthy, is actively recruiting participants, sponsored by University of California, Davis.

RECRUITING
Registry status
Phase 1
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1. Investigate whether ketoconazole cream, a commonly used topical antifungal, causes alterations in the human skin microbiome with short-term use. 2. Investigate whether desonide 0.05 % ointment, a commonly used low potency topical steroid, alters the human microbiome with short-term use.

Conditions Studied

Interventions

  • DRUG Desonide 0.05%
  • DRUG Ketoconazole 2%

Study Locations (1)

California

  • University of California, Davis, Department of Dermatology - Sacramento

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2013-01-28
Est. Completion 2026-09-28
Phase Phase 1

Sponsor

University of California, Davis

657 total trials

What the Registry Record Tells You About NCT03437005

The ClinicalTrials.gov registry entry for NCT03437005 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (96% lower). The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Desonide 0.05% is the first listed.

NCT03437005 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03437005 about?

NCT03437005 is a clinical study titled "Alternation in the Human Microbiome With Commonly Used Topical Medications". The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1. Investigate whether ketoconazole cream, a commo...

What is the current status of trial NCT03437005?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2013-01-28. Estimated completion is 2026-09-28.

What conditions does trial NCT03437005 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT03437005?

The interventions under investigation include: Desonide 0.05% (DRUG), Ketoconazole 2% (DRUG).

Who is sponsoring clinical trial NCT03437005?

This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03437005 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.