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NCT03437005 · ClinicalTrials.gov registry record · Phase 1
Alternation in the Human Microbiome With Commonly Used Topical Medications
A Phase 1 study of Healthy, sponsored by University of California, Davis.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT03437005: Recruiting Phase 1 study of Healthy, sponsored by University of California, Davis.
NCT03437005 is a Phase 1 study of Healthy that is actively recruiting participants, run by University of California, Davis. The registered enrollment target is 24 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03437005, a Phase 1 study of Healthy, is actively recruiting participants, sponsored by University of California, Davis.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1. Investigate whether ketoconazole cream, a commonly used topical antifungal, causes alterations in the human skin microbiome with short-term use. 2. Investigate whether desonide 0.05 % ointment, a commonly used low potency topical steroid, alters the human microbiome with short-term use.
Primary Outcome
Percentage of various bacteria present on each skin site
Conditions Studied
Interventions
- DRUG Desonide 0.05%
- DRUG Ketoconazole 2%
Study Locations (1)
California
- University of California, Davis, Department of Dermatology - Sacramento
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2013-01-28 |
| Est. Completion | 2026-09-28 |
| Phase | Phase 1 |
What NCT03437005 shows while recruiting
NCT03437005 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Desonide 0.05% is the first listed.
NCT03437005 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT03437005 about?
NCT03437005 is a clinical study titled "Alternation in the Human Microbiome With Commonly Used Topical Medications". The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1. Investigate whether ketoconazole cream, a commo...
What is the current status of trial NCT03437005?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2013-01-28. Estimated completion is 2026-09-28.
What conditions does trial NCT03437005 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT03437005?
The interventions under investigation include: Desonide 0.05% (DRUG), Ketoconazole 2% (DRUG).
Who is sponsoring clinical trial NCT03437005?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03437005 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03437005's enrollment target sits among peer trials
24 791st of 1090 higher than 254 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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