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NCT03419273 · ClinicalTrials.gov registry record
Adipose Tissue Inflammation in Individuals Undergoing Bariatric Surgery
A clinical trial, sponsored by University of Missouri-Columbia.
- Completed
- Registry status
- 84
- Enrollment target
NCT03419273: Completed study, sponsored by University of Missouri-Columbia.
NCT03419273 is a clinical trial that has completed, run by University of Missouri-Columbia. The registered enrollment target is 84 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03419273 has completed, sponsored by University of Missouri-Columbia.
- COMPLETED
- Registry status
- 84 participants
- Enrollment target
Study Summary
A growing body of work done over the past few decades has established that adipose tissue as an active endocrine organ which secretes a wide range of metabolic and immunological factors collectively called "adipokines (1)." Importantly, these secreted factors enter into the circulation and have paracrine and autocrine actions, which profoundly impact systemic metabolism (e.g., insulin sensitivity). Additionally, in animals, loss of ovarian hormone production via ovariectomy (similar to menopause in humans) leads to increases in both in adipose tissue mass and in adipose tissue inflammation (2) making this tissue less healthy than that from premenopausal animals. To date, no studies have investigated the effect of menopause on abdominal fat in overweight individuals. Knowing if adipose tissue-specific changes occur with menopause may potentially lead to recommendations or therapeutics to improve women's health post menopause.
Primary Outcome
TNFa
Interventions
- PROCEDURE bariatric surgery
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2017-07-01 |
| Est. Completion | 2019-07-01 |
What the finished NCT03419273 record still lists
NCT03419273 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 84 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which bariatric surgery is the first listed.
NCT03419273 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03419273 about?
NCT03419273 is a clinical study titled "Adipose Tissue Inflammation in Individuals Undergoing Bariatric Surgery". A growing body of work done over the past few decades has established that adipose tissue as an active endocrine organ which secretes a wide range of metabolic and immunological factors collectively called "adipokines (1)." Importantly, these secreted factors enter into the circulation and have para...
What is the current status of trial NCT03419273?
This trial is currently completed. The enrollment target is 84 participants. The study started on 2017-07-01. Estimated completion is 2019-07-01.
What interventions are being tested in trial NCT03419273?
The interventions under investigation include: bariatric surgery (PROCEDURE).
Who is sponsoring clinical trial NCT03419273?
This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.
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