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ACTIVE NOT RECRUITING Phase 2

Atezolizumab + Pertuzumab + Trastuzumab In CNS Mets In BC

NCT03417544 · View on ClinicalTrials.gov ↗

Study Summary

This research study is studying a drug called atezolizumab as a possible treatment HER2-positive metastatic breast cancer (MBC) that has spread to the brain. The names of the study drugs involved in this study are: * Atezolizumab * Pertuzumab * Trastuzumab

Interventions

  • DRUG ATEZOLIZUMAB
  • DRUG PERTUZUMAB
  • DRUG TRASTUZUMAB

Study Locations (2)

Illinois

  • Northwestern University — Chicago

Massachusetts

  • Dana-Farber Cancer Institute — Boston

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2018-05-21
Est. Completion 2025-12
Phase Phase 2

Sponsor

Nancy Lin, MD

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03417544

The ClinicalTrials.gov registry entry for NCT03417544 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Nancy Lin, MD, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with HER2-positive Metastatic Breast Cancer appearing as the primary indexed condition, and to 3 interventions — of which ATEZOLIZUMAB is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03417544 reports 2 study locations spanning 2 distinct geographic areas — top geographies include Illinois, Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03417544 about?

NCT03417544 is a clinical study titled "Atezolizumab + Pertuzumab + Trastuzumab In CNS Mets In BC". This research study is studying a drug called atezolizumab as a possible treatment HER2-positive metastatic breast cancer (MBC) that has spread to the brain. The names of the study drugs involved in this study are: * Atezolizumab * Pertuzumab * Trastuzumab

What is the current status of trial NCT03417544?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 19 participants. The study started on 2018-05-21. Estimated completion is 2025-12.

What conditions does trial NCT03417544 study?

This clinical trial studies the following conditions: HER2-positive Metastatic Breast Cancer, Central Nervous System Metastases. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03417544?

The interventions under investigation include: ATEZOLIZUMAB (DRUG), PERTUZUMAB (DRUG), TRASTUZUMAB (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03417544?

This trial is sponsored by Nancy Lin, MD, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03417544 being conducted?

This trial has 2 study locations across Illinois, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial