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NCT03414138 · ClinicalTrials.gov registry record · NA

Brain Mechanisms Supporting Meditation-based Analgesia

A NA study of Pain, sponsored by University of California, San Diego.

Completed
Registry status
NA
Development phase
40
Enrollment target
1
Study location

NCT03414138: Completed NA study of Pain, sponsored by University of California, San Diego.

NCT03414138 is a NA study of Pain that has completed, run by University of California, San Diego. The registered enrollment target is 40 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03414138, a NA study of Pain, has completed, sponsored by University of California, San Diego.

COMPLETED
Registry status
NA
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

Mindfulness meditation has been shown to reduce pain in experimental and clinical settings, and the neural mechanisms underlying this analgesia are distinct from that of placebo related beliefs in the utility of the meditation. Although previous studies have identified potential cortical and sub-cortical targets responsible for mediating these effects, the connectional relationships between them remains largely unexplored. The present study will use blood-oxygen-level dependent (BOLD) neuroimaging to assess functional connections supporting mindfulness meditation.

Primary Outcome

Changes in blood oxygenation levels to thermally noxious stimuli (49°C) will be assessed, and planned comparisons will be performed between subjects trained in mindfulness meditation and those trained in deep-breathing meditation.

Conditions Studied

Interventions

  • BEHAVIORAL Mindfulness Training
  • BEHAVIORAL Book Listening Control

Study Locations (1)

North Carolina

  • Wake Forest University Health Sciences - Winston-Salem

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2018-04-20
Est. Completion 2018-08-02
Phase NA
University of California, San Diego

775 total trials

What the finished NCT03414138 record still lists

NCT03414138 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (87% lower).

The record links to 1 condition, with Pain appearing as the primary indexed condition, and to 2 interventions - of which Mindfulness Training is the first listed.

NCT03414138 reports a single indexed study location in North Carolina.

Frequently Asked Questions

What is clinical trial NCT03414138 about?

NCT03414138 is a clinical study titled "Brain Mechanisms Supporting Meditation-based Analgesia". Mindfulness meditation has been shown to reduce pain in experimental and clinical settings, and the neural mechanisms underlying this analgesia are distinct from that of placebo related beliefs in the utility of the meditation. Although previous studies have identified potential cortical and sub-cor...

What is the current status of trial NCT03414138?

This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2018-04-20. Estimated completion is 2018-08-02.

What conditions does trial NCT03414138 study?

This clinical trial studies the following conditions: Pain.

What interventions are being tested in trial NCT03414138?

The interventions under investigation include: Mindfulness Training (BEHAVIORAL), Book Listening Control (BEHAVIORAL).

Who is sponsoring clinical trial NCT03414138?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03414138 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03414138's enrollment target sits among peer trials

40 282nd of 374 higher than 85 of 374 other Pain trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03414138, the US trial registry maintained by the National Library of Medicine. NCT03414138 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.