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NCT03412981 · ClinicalTrials.gov registry record

Obesity and Adipose Tissue Inflammation in Pregnant Mothers

A clinical trial, sponsored by University of Missouri-Columbia.

Completed
Registry status
27
Enrollment target

NCT03412981: Completed study, sponsored by University of Missouri-Columbia.

NCT03412981 is a clinical trial that has completed, run by University of Missouri-Columbia. The registered enrollment target is 27 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03412981 has completed, sponsored by University of Missouri-Columbia.

COMPLETED
Registry status
27 participants
Enrollment target

Study Summary

To date very little research has been conducted on pregnant mothers. Research shows that mothers with obesity and gestational diabetes have children who have a higher risk of later developing obesity and diabetes compared to children born to non-obese mothers but the mechanisms are not known. The maternal environment may place these babies at greater risk and it is possible that fat tissue (adipose tissue) releases many chemicals (adipokines and inflammatory cytokines) which may have an impact on the baby. Mothers who have greater amounts of adipose tissue most likely release these adipokines into the baby and it may affect the baby's body composition and/or health. This project will establish if there is a relationship between obesity and adipose tissue inflammation in pregnant mothers, and if there is a link between inflammation and the child's body composition. We will recruit mothers with low risk pregnancies already schedule for a C section at about 36 wk. We will do initial testing at 36 wk, adipose tissue collection at delivery, and conduct post testing at 1 month postpartum on the mother and the baby.

Primary Outcome

TNFa, IL-6, IL-4, IL-13

Interventions

  • OTHER pregnant mothers

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2017-12-01
Est. Completion 2020-10-31
University of Missouri-Columbia

291 total trials

What the finished NCT03412981 record still lists

NCT03412981 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 27 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which pregnant mothers is the first listed.

NCT03412981 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03412981 about?

NCT03412981 is a clinical study titled "Obesity and Adipose Tissue Inflammation in Pregnant Mothers". To date very little research has been conducted on pregnant mothers. Research shows that mothers with obesity and gestational diabetes have children who have a higher risk of later developing obesity and diabetes compared to children born to non-obese mothers but the mechanisms are not known. The ma...

What is the current status of trial NCT03412981?

This trial is currently completed. The enrollment target is 27 participants. The study started on 2017-12-01. Estimated completion is 2020-10-31.

What interventions are being tested in trial NCT03412981?

The interventions under investigation include: pregnant mothers (OTHER).

Who is sponsoring clinical trial NCT03412981?

This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT03412981, the US trial registry maintained by the National Library of Medicine. NCT03412981 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.