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NCT03400475 · ClinicalTrials.gov registry record · Phase 2
Use of Topical Subgingival Application of Simvastatin Gel in the Treatment of Peri-Implant Mucositis
A Phase 2 study of Peri-implant Mucositis, sponsored by Ahmed Mohamed Mahrous.
- Completed
- Registry status
- Phase 2
- Development phase
- 46
- Enrollment target
- 1
- Study location
NCT03400475 is a Phase 2 study of Peri-implant Mucositis that has completed, run by Ahmed Mohamed Mahrous. The registered enrollment target is 46 participants. The trial reports 1 study location across 1 state.
The verdict
NCT03400475, a Phase 2 study of Peri-implant Mucositis, has completed, sponsored by Ahmed Mohamed Mahrous.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 46 participants
- Enrollment target
- 1
- Study location
Study Summary
This study seeks to test the recently discovered anti-inflammatory action of statins on inflamed mucosa surrounding dental implants. Hypothesis: The application of 1.2% simvastatin gel will decrease peri-implant inflammation. The pilot study will involve 44 subjects divided into a test and control group. The test group shall receive topical simvastatin gel administered around the implant with a blunt tipped needle. The control group will receive a placebo. Inflammatory state shall be determined at baseline as well as follow up visits at 24 hours, 1 week, and 1 month by clinical indices of inflammation as well as biochemical markers of inflammation gathered from around the implants.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Simvastatin
Study Locations (1)
Iowa
- University of Iowa College of Dentistry and Dental Clinics - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2015-04-23 |
| Est. Completion | 2016-10-24 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03400475
The ClinicalTrials.gov registry entry for NCT03400475 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 46 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Ahmed Mohamed Mahrous, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Peri-implant Mucositis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT03400475 reports 1 study location spanning 1 distinct geographic area - top geographies include Iowa.
Frequently Asked Questions
What is clinical trial NCT03400475 about?
NCT03400475 is a clinical study titled "Use of Topical Subgingival Application of Simvastatin Gel in the Treatment of Peri-Implant Mucositis". This study seeks to test the recently discovered anti-inflammatory action of statins on inflamed mucosa surrounding dental implants. Hypothesis: The application of 1.2% simvastatin gel will decrease peri-implant inflammation. The pilot study will involve 44 subjects divided into a test and control...
What is the current status of trial NCT03400475?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 46 participants. The study started on 2015-04-23. Estimated completion is 2016-10-24.
What conditions does trial NCT03400475 study?
This clinical trial studies the following conditions: Peri-implant Mucositis.
What interventions are being tested in trial NCT03400475?
The interventions under investigation include: Placebo (OTHER), Simvastatin (DRUG).
Who is sponsoring clinical trial NCT03400475?
This trial is sponsored by Ahmed Mohamed Mahrous, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03400475 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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